2-(6-Methyl-1-benzofuran-3-yl)acetic acid

Abstract

The asymmetric unit of the title compound, C11H10O3, contains two crystallographically independent molecules (AandB) with nearly matching conformations. Both molecules are almost planar [r.m.s. overlay fit for the non-hydrogen atoms = 0.011 (1) Å] and in each molecule there is a short intramolecular C—H...O contact. In both molecules, the OH group of the acetic acid residue occupies a position approximately antiperiplanar to the C atom of the heterocycle. In the crystal, the two molecules are linked by a pair of O—H...O hydrogen bonds, enclosing anR22(8) ring motif and forming anA–Bdimer. The dimers are linked by C—H...π interactions, forming columns along the [010] direction.

2-(4,6-Dimethyl-1-benzofuran-3-yl)acetic acid

“…As part of our studies in this area, we now report the crystal structure of the title compound. All the bond lengths and angles are close to those observed for similar structures (Gowda et al, 2015;Ramprasad et al, 2016).…”

2-(5-Methyl-1-benzofuran-3-yl)-N-(2-phenylethyl)acetamide

“…deviation from the plane through the ten atoms of the benzofuran ring system is 0.011 Å . The molecular structure is similar to that observed for 2-(5-methyl-1-benzofuran-3-yl)-acetic acid (Ramprasad et al, 2016).…”