In this study, a high-efficiency, high-power synchronous rectifier based on transistors was designed. The widely used diode-based rectifiers have a relatively simple structure but are unsuitable for high-power applications, such as unmanned aerial vehicle and electric vehicle charging. In contrast, transistor-based rectifiers operate by reversing the power flow of a switch-mode power amplifier from the load to the DC supply based on time-reversal duality and can rectify efficiently, even at a high power of 30 dBm or more. The proposed transistor-based synchronous rectifier was designed to have a high rectification efficiency by controlling the harmonics to operate in the inverse Class-F mode and achieved a peak efficiency of 73.2% at an input power of 37 dBm.