2,2-Diphenyl-4-(piperidin-1-yl)butanamide

Abstract

In the title compound, C21H26N2O, the dihedral angle between the mean planes of the two benzene rings is 81.1 (9)°. The piperidine ring is in a chair conformation. The crystal packing is stabilized by N—H⋯N and N—H⋯O hydrogen bonds and weak inter­molecular C—H⋯O inter­actions.

Vibrational spectra, HOMO, LUMO, NBO, MEP analysis and molecular docking study of 2,2-diphenyl-4-(piperidin-1-yl)butanamide

“…The crystal structures of N,N-diphenylacetamide [13], 4,4 0 -dime thylbiphenyl-2,2 0 -dicarboxylic acid [14], 4 0 -methylbiphenyl-2-car boxylic acid [15] and 4 0 -(2-butyl-4-chloro-5-formylimidazol-1-yl methyl) biphenyl-2-carbonitrile [16], 2-hydroxy-N-(3-oxo-1-thi a-4-azaspiro [4,5]dec-4-yl)2,2-diphenylacetamide [17] and 2-chlor o-N-[4-chloro-2(2-chlorobenzoyl)phenyl]acetamide [18] have been reported. The crystal structure of the title compound is reported by Siddegowda et al [19]. In the present work, FT-IR and FT-Raman spectra of the title compound were reported both experimentally and theoretically.…”