{2-[(2-Carbamothiolylhydrazin-1-ylidene-κ²N¹,S)methyl]-6-hydroxyphenolato-κO¹}(triphenylphosphine-κP)nickel(II) chloride

Abstract

The deprotonated Schiff base ligand in the title compound, [Ni(C8H8N3O2S)(C18H15P)]Cl, functions as an N,O,S-chelating anion to the phosphine-coordinated Ni atom, which exists in a distorted square-planar geometry. The hy­droxy group forms an intra­molecular O—H⋯O hydrogen bond. The two amino groups of the cation are hydrogen-bond donors to the chloride anion; the hydrogen bonds generate a chain structure running along the b axis.

Nickel(II) Complex of Polyhydroxybenzaldehyde N4-Thiosemicarbazone Exhibits Anti-Inflammatory Activity by Inhibiting NF-κB Transactivation

“…The most significant IR bands for nickel(II) phosphine mixed complexes of 2,3-dihydroxybenzaldehyde-N4-subsituted thiosemicarbazone were collected with their tentative assignments ( Table 1 ). The crystal structures of complexes 5 and 6 have been described previously [20] , [21] . The title complexes 7 and 8 crystallized into orthorhombic crystal system.…”

“…The thiosemicarbazone ligands H 3 L( 1–4 ) were prepared following the published procedure [19] by reaction of 2,3-dihydroxybenzaldehyde with thiosemicarbazide (H 3 L 1 ; ligand 1 ), 4-methyl-3-thiosemicarbazide (H 3 L 2 ; ligand 2 ), 4-phenyl-3-thiosemicarbazide (H 3 L 3 ; ligand 3 ) and 4-ethyl-3-thiosemicarbazide (H 3 L 4 ; ligand 4 ) in a 1: 1 molar ratio, under standard reflux conditions. Complexes ( 5–8 ) were synthesized according to the published works [20] , [21] . Complexes [Ni(H 2 L 1 )(PPh 3 )]Cl ( 5 ), [Ni(H 2 L 2 )(PPh 3 )] ( 6 ), [Ni(HL 3 )(PPh 3 )] ( 7 ) and [Ni(HL 4 )(PPh 3 )] ( 8 ) were also named as complex 5 , 6 , 7 and 8 below.…”