2‐(1 H‐1,2,3‐Triazol‐4‐yl)‐Pyridine Ligands as Alternatives to 2,2′‐Bipyridines in Ruthenium(II) Complexes

Abstract

The synthesis of a variety of 2-(1H-1,2,3-triazol-4-yl)-pyridines by click chemistry is demonstrated to provide straightforward access to mono-functionalized ligands. The ring-opening polymerization of epsilon-caprolactone initiated by such a mono-functionalized ligand highlights the synthetic potential of this class of bidentate ligands with respect to polymer chemistry or the attachment onto surfaces and nanoparticles. The coordination to Ru(II) ions results in homoleptic and heteroleptic complexes with the resultant photophysical and electrochemical properties strongly dependent on the number of these ligands attached to the Ru(II) core.

Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes

“…Supplementary Materials: The following are available online at www.mdpi.com/1420-3049/21/10/1382/s1, Figure S1: 1 H-NMR spectrum of 1 (CD 3 CN), Figure S2: 13 C-NMR spectrum of 1 (CD 3 CN), Figure S3: ESI mass spectrum of 1, Figure S4: 1 H-NMR spectrum of 1 Cl (d 6 -DMSO), Figure S5: 13 C-NMR spectrum of 1 Cl (d 6 -DMSO), Figure S6: ESI mass spectrum of 1 Cl , XYZ coordinates for the optimized geometries of the ground and lowest lying triplet states of 1, Figure S7: Time-dependent DFT UV-visible absorption spectrum of 1, Table S1: Summarised time-dependent DFT data for 1.…”

“…We, and others, have paid particular attention to the use of copper-catalysed coupling of alkynes and azides to form 1,2,3-triazole-based ligands [7][8][9][10] and have investigated the photophysical properties of their resultant complexes. A significant number of reports have appeared detailing the photophysical and photochemical properties of triazole-based complexes of Re(I), Ru(II) and Ir(III) [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Examples of triazole-containing complexes of osmium(II)…”

Copper(I) Complexes of Normal and Abnormal Carbenes and Their Use as Catalysts for the Huisgen [3+2] Cycloaddition between Azides and Alkynes

“…Cycloaddition reaction with an internal alkyne was also achieved with these catalysts. Finally a bulky azide was used as a substrate to prepare compound 1-(2,6-dimesityl)phenyl-4-(2-pyridyl)-1,2,3-triazole (14) with the above mentioned copper catalysts. Such bulky azides are usually unreactive towards cycloaddition reactions with alkynes in the presence of the Cu II /ascorbate/tbta catalytic system.…”

Rhenium(I) and technetium(I) complexes of a novel pyridyltriazole-based ligand containing an arylpiperazine pharmacophore: Synthesis, crystal structures, computational studies and radiochemistry

“…The mild reaction conditions associated with the synthetic click approach allowed the preparation of a large number of mono-functionalized pyta derivatives. Nevertheless, only a few of them possess a tethering group for further coupling to a biomolecule [5,6], and one example of pyta grafted on a bioactive molecule (a glucose scaffold) was reported [7].…”