1H NMR study on the solvent effect on imine-enamine tautomerism of the condensation product of gossypol with 4-aminoantipyrine

Theoretical and experimental 15N NMR study of enamine–imine tautomerism of 4‐trifluoromethyl[b]benzo‐1,4‐diazepine system

“…One of the most interesting and intrinsic aspects of this type of heterocycles is the existence of several tautomeric forms. Usually, the enamine form predominates with increase in the dielectric constant of the medium . It should be expected that enamine–imine tautomeric equilibrium is shifted toward a more conjugated system having the lowest overall energy.…”