2021
DOI: 10.5489/cuaj.7107
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18F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) is accurate for high-grade prostate cancer bone staging when compared to bone scintigraphy

Abstract: Introduction: In this study, we compared 18F-FDG-postron emission tomography/computed tomography (PET/CT) and bone scintigraphy accuracies for the detection of bone metastases for primary staging in high-grade prostate cancer (PCa) patients to determine if 18F-FDG-PET/CT could be used alone as a staging modality. Methods: Men with localized high-grade PCa (n=256, Gleason 8–10, International Society of Urological Pathology [ISUP] grades 4 or 5) were imaged with bone scintigraphy and 18F-FDG-PET/CT. We com… Show more

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Cited by 6 publications
(2 citation statements)
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“…18 F-FDG-PET/CT is also of great value in the diagnosis of bone metastases in high-grade PCa patients (GS≥8). In comparison with the bone scan, 18 F-FDG PET/CT is sensitive and accurate in detecting bone metastases (sensitivity:100% vs 78.8%, specificity: 98.7% vs 98.2%) ( 49 ).…”
Section: Additional Pet Agents For Pca Diagnosismentioning
confidence: 99%
“…18 F-FDG-PET/CT is also of great value in the diagnosis of bone metastases in high-grade PCa patients (GS≥8). In comparison with the bone scan, 18 F-FDG PET/CT is sensitive and accurate in detecting bone metastases (sensitivity:100% vs 78.8%, specificity: 98.7% vs 98.2%) ( 49 ).…”
Section: Additional Pet Agents For Pca Diagnosismentioning
confidence: 99%
“…In this edition of CUAJ, Otis-Chapados et al performed a retrospective study of 256 patients undergoing primary staging for high-grade (International Society of Urological Pathology [ISUP] ≥4) prostate cancer. 1 All patients underwent a bone scan and an FDG PET/computed tomography (CT). They analyzed the imaging results as a function of the "standard of truth."…”
mentioning
confidence: 99%