[18F]FDG PET-CT in the diagnosis of bacterial pericarditis

Borges-Rosa, J; Oliveira-Santos, Manuel; Silva, Rodolfo; Mendes, Jorge; Madaleno, João; Teixeira, Rogério; Ferreira, Maria João; Gonçalves, Lino

doi:10.1007/s12350-021-02706-7

Cited by 1 publication

(2 citation statements)

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“…PET-CT has had an increasing role in the identification of several infections, including CDRIE [ 20 ]. PET/CT is probably insufficient for the diagnosis of IE, but it can be useful for the diagnosis of PV endocarditis and skin or ICED pocket infections [ 20 , 22 ]. PET/CT as a diagnostic tool for CDRIE had 87% sensitivity and 94% specificity in a recent meta-analysis [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

“…In particular, the sensitivity and specificity for pocket infections were 93% and 98%, respectively, whereas sensitivity and specificity for the lead were 65% and 88%, respectively. It is of note that regarding contraindications of PET/CT only pregnancy is considered an absolute one, while others such as obesity may reduce image quality and interpretation [ 22 ]. Therefore, PET/CT may contribute significantly to the diagnosis of CDRIE as in the present case.…”

Section: Discussionmentioning

confidence: 99%

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Contribution of Positron Emission Tomography-Computed Tomography (PET/CT) to the Diagnosis of Endocarditis Due to an Infected Pacemaker Associated With Spondylodiscitis

Kalkinis¹,

Vassilopoulos²,

Rokas³

et al. 2023

Cureus

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The incidence of cardiac device-related endocarditis (CDRIE) is increasing, and its diagnosis and treatment may occasionally be problematic. Echocardiography is important for its diagnosis, and 18F-fluorodeoxyglucose positron emission tomography-computed tomography (PET/CT) may also be useful as a diagnostic procedure. A case of CDRIE due to an infected pacemaker is presented. In this case, blood cultures were repeatedly negative, and transesophageal ultrasound examination did not reveal signs of the disease. However, PET/CT revealed the infection. The causative organism was Corynebacterium spp, and this was finally identified by polymerase chain reaction of a sample of the device material. Eight weeks before the development of CDRIE symptoms, the patient had been empirically treated for spondylodiscitis caused by a non-identified organism. CDRIE and spondylodiscitis are closely associated infections. The present case of CDRIE was treated successfully with six weeks of combination antimicrobial treatment. PET/CT may contribute to CDRIE diagnosis by locating the site(s) of the infection, especially in cases that are ultrasound and culture negative.

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