18F-FDG PET/CT in Extranodal Burkitt Lymphoma

Abstract

Burkitt lymphoma (BL) is a poorly differentiated non-Hodgkin B-cell lymphoma, more frequent in children than in adults. The extranodal debut of the disease is rare. We report a 43-year-old male patient with history of dyspnea. Burkitt lymphoma diagnosis was reached after biopsy of a pleural lesion. An initial staging F-FDG-PET/CT revealed large high-uptake lymphatic clusters in mediastinum, lung hilum, and extranodal involvement in pleura, pericardium, periphery of liver and spleen, all the omentum and peritoneum down to the pelvic floor, and bone marrow infiltration.

Peritoneal super scan on 18F - FDG PET-CT in a patient of burkitt's lymphoma

“…[123] FDG uptake has been reported in peritoneal lymphomatosis both in DLBCL and Burkitt's lymphoma. [456] Our case illustrates intense FDG uptake involving the entire peritoneum with suppressed FDG activity of the rest of the body including brain and kidneys, giving it an appearance of “super scan.” Skeletal and hepatic super scans have already been mentioned in the literature in lympho-reticular malignancies. [789] To our knowledge, such “peritoneal super scan” has not been reported till date.…”

Diagnostic Value of PET/MR with DWI for Burkitt Lymphoma

“…Burkitt lymphoma of the bone marrow occurs in around 30% of the cases and is usually associated with poor prognosis. Whole-body techniques, such as computed tomography (CT) and 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/CT are crucial in the diagnostic process [2,4,5]. In the latter in particular, providing metabolic information is very useful for detecting both nodal and extra-nodal lesions, predicting the outcome, and evaluating the response to treatment.…”