18F-FDG PET/CT for the evaluation of male breast cancer: a systematic review

Dondi, Francesco; Albano, Domenico; Giubbini, Raffaele; Bertagna, Francesco

doi:10.1097/mnm.0000000000001508

Cited by 3 publications

(2 citation statements)

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“…In a systematic review by Dondi [ 41 ], which aimed to analyze the diagnostic performance and utility of 18F-FDG PET/CT in the evaluation of MBC, it was found that, despite the limitations of the review, 18F-FDG PET/CT appears to be an effective method for assessing MBC. The conclusion continued with the idea that further research is required to clarify the role of hybrid imaging with 18F-FDG in the evaluation of MBC, particularly in comparison to breast cancer in females.…”

Section: Resultsmentioning

confidence: 99%

An Update on the General Features of Breast Cancer in Male Patients—A Literature Review

et al. 2022

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Male breast cancers are uncommon, as men account for less than 1 percent of all breast carcinomas. Among the predisposing risk factors for male breast cancer, the following appear to be significant: (a) breast/chest radiation exposure, (b) estrogen use, diseases associated with hyper-estrogenism, such as cirrhosis or Klinefelter syndrome, and (c) family health history. Furthermore, there are clear familial tendencies, with a higher incidence among men who have a large number of female relatives with breast cancer and (d) major inheritance susceptibility. Moreover, in families with BRCA mutations, there is an increased risk of male breast cancer, although the risk appears to be greater with inherited BRCA2 mutations than with inherited BRCA1 mutations. Due to diagnostic delays, male breast cancer is more likely to present at an advanced stage. A core biopsy or a fine needle aspiration must be performed to confirm suspicious findings. Infiltrating ductal cancer is the most prevalent form of male breast cancer, while invasive lobular carcinoma is extremely uncommon. Male breast cancer is almost always positive for hormone receptors. A worse prognosis is associated with a more advanced stage at diagnosis for men with breast cancer. Randomized controlled trials which recruit both female and male patients should be developed in order to gain more consistent data on the optimal clinical approach.

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Section: Resultsmentioning

confidence: 99%

An Update on the General Features of Breast Cancer in Male Patients—A Literature Review

et al. 2022

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“…18 F-fluorodeoxyglucose ([ 18 F]FDG) is the most common radiotracer used to perform positron emission tomography/CT (PET/CT) and PET/MRI. At first, this tracer was used mainly for the assessment of neoplastic diseases, given its ability to detect hypermetabolic lesions on the basis of their glycolytic metabolism [ 5 , 6 , 7 , 8 , 9 , 10 , 11 ]. However, high glucose metabolism characterizes also activated inflammatory cells, and the use of [ 18 F]FDG PET has emerged for the evaluation of infectious and inflammatory diseases [ 12 , 13 , 14 , 15 , 16 , 17 , 18 ].…”

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confidence: 99%