181. 2-p-Aminobenzenesulphonamidopyrimidines. Preparation by a novel route

Rose, F. L.; Swain, G.

doi:10.1039/jr9450000689

Cited by 10 publications

(3 citation statements)

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“…18 Although structuralist approaches such as Genette's provided a comprehensive model of parody, as is often the accusation made against structuralism they failed to take social and historical influences into account. 19 Moreover, structuralist approaches to parody tend not to place much emphasis on the audience since their critical lens turns to the relations between texts. As might be expected, poststructuralist research on parody and satire, however, focuses explicitly on the audience's active involvement within the process of interpretation.…”

Section: -Section One: Historical Contexts For Parody and Cultural Prmentioning

confidence: 99%

Parody: Affective Registers, Amateur Aesthetics and Intellectual Property

Milne

2013

CSR

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If contemporary media platforms transform and conflate the relations between professional and amateur creative workers, what might we say about the specificity of their vernacular? This article argues that parody is a key site for the articulation of amateur labour enabled by new patterns of networked production and consumption. Despite its utopian promise of free speech, however, the parodic form is tempered by economic and legal exigencies. Therefore, the essay particularly investigates legislative and policy frameworks that constrain parody discourse. Amendments in 2006 to the Australian Copyright Act 1968 (Cth), for example, introduced parody and satire defences allowing greater scope for social critique. Yet recent US legislation preventing online impersonation (such as mock twitter accounts) raises crucial questions about the public domain.

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Section: -Section One: Historical Contexts For Parody and Cultural Prmentioning

confidence: 99%

Parody: Affective Registers, Amateur Aesthetics and Intellectual Property

Milne

2013

CSR

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“…Different approaches have been reported in the synthesis of sulfapyrimidine derivatives. The condensation reaction of B ‐diketones or B ‐ketocarboxylic esters with arylsulfonyl guanidine is a well‐known reaction for the preparation of sulfapyrimidine derivatives . Another approach for the synthesis of sulfapyrimidine derivatives is by reacting different 2‐aminopyrimidines to arylsulfonyl chloride .…”

Section: Introductionmentioning

confidence: 99%

Tailored‐design Synthesis of Sulfapyrimidine Derivatives

Azzam

2018

Journal of Heterocyclic Chem

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In this paper, we report an efficient and convenient approach for the synthesis of tailored‐design target sulfapyrimidine derivatives expected to show remarkable antimicrobial activities. The approach is based on reacting arylsulfonyl guanidine with α,β‐unsaturated carbonyl compounds to afford N‐(4,6‐diarylpyrimidin‐2‐yl)arylsulfonamide or with ylidene derivatives to afford N‐(6‐aryl‐5‐cyanopyrimidin‐2‐yl)arylsulfonamide, N‐(4‐amino‐5‐cyano‐6‐(methylthio)‐pyrimidin‐2‐yl)‐arylsulfonamide, and N‐(5‐cyanopyrimidin‐2‐yl)arylsulfonamide compounds through Michael addition reaction. The structure of the newly synthesized compounds was confirmed from spectral data and elemental analysis.

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“…In this way, it was possible to obtain good yields of the desired products. Consecutive steps were performed according to a standard reaction protocol 13 (Scheme 2). Using this precursor (7), 8 was synthesized in 100% yield as a "cold" reference For the radiosynthesis a Hotbox III remote controlled synthesis module was used.…”

Section: Synthesis Via Condensation Of the Guanidyl Compoundmentioning

confidence: 99%

The facile synthesis of a pyrimidinyl sulfonamide (N,N,N,6-tetramethyl-2-(4-nitrophenylsulfonamido)pyrimidin-4-ammonium chloride) as a PET tracer precursor

Gebhardt¹,

Saluz²

2012

Arkivoc

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We synthesized the novel sulfonamide derivative, N,N,N,6-tetramethyl-2-(4-nitrophenylsulfonamido)pyrimidin-4-ammonium chloride (7), for use as a precursor in [ 18 F]fluoride chemistry. For this, 4-nitrobenzenesulfonyl guanidine was used as the starting material for condensation with ethyl acetoacetate. The 19 F-compound could be synthesized in four steps with moderate yields. The 18 F-labelled analogue, which has high potential as an intermediate for a positron emission tomography tracer, was produced with a radiochemical yield of 58±12% (n = 4, decay corrected).

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181. 2-p-Aminobenzenesulphonamidopyrimidines. Preparation by a novel route

Abstract: The preparation is described of a series of sulphanilamide derivatives of pyrimidine by allowing p-nitro-, p-amino-or p-acetaddo-benzenesulphonylguanidine t o react with /I-diketones or b-ketocarboxylic esters.

Cited by 10 publications

References 0 publications

Parody: Affective Registers, Amateur Aesthetics and Intellectual Property

Parody: Affective Registers, Amateur Aesthetics and Intellectual Property

Tailored‐design Synthesis of Sulfapyrimidine Derivatives

The facile synthesis of a pyrimidinyl sulfonamide (N,N,N,6-tetramethyl-2-(4-nitrophenylsulfonamido)pyrimidin-4-ammonium chloride) as a PET tracer precursor

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