180 Immunophenotypic Analysis of Erythroid Dysplasia in Myelodysplastic Syndromes. A Report on Behalf of the International and European Leukemianet Imds-Flow Working Group

A series of case studies illustrating the role of flow cytometry in the diagnostic work‐up of myelodysplastic syndromes

“…Monocytes were <0.1%. Increased erythropoiesis was identified; using the four key parameters identified by the ELN iMDS‐Flow group to assess dysplasia (Westers et al, 2017), multiple dysplastic features were seen: increased CD71 CV (coefficient of variation), reduced CD71 expression, decreased erythroid progenitors as percentage of total erythroid cells, and the CD36 percentage was barely within the expected range. An Ogata score of 4 together with the presence of FCM aberrancies supported the diagnosis of MDS (Cremers et al, 2017; Della Porta et al, 2012).…”