“…In pursuit to unravel possible mechanism of action of 2-ME, several molecular targets including reactive oxygen species (Lin et al, 2000), cell cycle kinases and regulators (Lottering et al, 1996;Zoubine et al, 1999), transcription factor modulators (Yue et al, 1997), p53, tubulin etc. (Mukhopadhyay and Roth, 1997;D'Amato et al, 1994;Hamel et al, 1996) have been proposed.…”