1729TiP Rationale and design of the phase IIb/III VOICE trial of clonidine MBT for the prevention of severe oral mucositis in patients with OPC receiving chemoradiotherapy

Abstract

and 15.0% of the patients presented 2 and 3 symptoms. The 4 most common symptoms were pain (16.2%), general weakness (12.3%), dyspnea (12.2%), and fever (11.3%). According to patients' situation, 59.2% of ED visits lead to hospitalization in inpatients units for a stay of 8.2 days in average. In multivariable analysis, different factors were associated with the admission: (1) time of the visit (between 19h-21h: