16622 Granulomatous reaction to microneedling

Demaree, Elizabeth; Cleaver, David; Cleaver, L.; Cleaver, Nathan; Cleaver, Jonathan

doi:10.1016/j.jaad.2020.06.357

Cited by 2 publications

(1 citation statement)

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“…This is a rare complication, with only 10 previous cases found upon review of the literature. [4][5][6][7][8][9][10][11] Soltani-Arabshahi et al originally described three similar cases of women who developed facial granulomas following microneedling, with evidence of foreign body-type granulomas on biopsy and a positive patch test reaction to vitamin C serum in two cases. They hypothesized that these cases represented true delayed-type hypersensitivity granulomas secondary to an immunologic response after intradermal tattooing of an antigenic topical product.…”

Section: Discussionmentioning

confidence: 99%

A case of a delayed granulomatous reaction on the face following microneedling: A case report

Heck

Traboulsi

2022

SAGE Open Medical Case Reports

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Background: Microneedling is a common non-invasive procedure used for a variety of dermatologic conditions. It is associated with a low rate of adverse events which are typically temporary. Hypersensitivity reactions, including granuloma formation, are a rare adverse event, with only 10 cases previously reported. Case Summary: We report a case of a 49-year-old female who presented with asymptomatic edematous erythematous annular plaques on her left cheek following a microneedling procedure in which a Vitamin C cosmeceutical was applied to the skin beforehand. Skin biopsy confirmed non-necrotizing granulomatous dermatitis with negative tissue cultures. Systemic workup for sarcoidosis was negative. Conclusion: Delayed facial granulomatous reaction is an uncommon adverse event following microneedling. Increased risk may be related to peri-procedure use of cosmeceuticals such as Vitamin C. Given the popularity of microneedling, and that it is an unregulated procedure, it is important for dermatologists to be aware of this possible sequela in order to counsel patients appropriately and understand management options.

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Section: Discussionmentioning

confidence: 99%

A case of a delayed granulomatous reaction on the face following microneedling: A case report

Heck

Traboulsi

2022

SAGE Open Medical Case Reports

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Microblading reaction as a manifestation of systemic sarcoidosis: two case reports and a review of the literature

Merzel Šabović,

Starbek Zorko,

Hosta

et al. 2024

J Med Case Reports

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Background Sarcoidosis is a multisystemic disease characterized by granulomatous inflammation. Sarcoidosis often poses a diagnostic challenge owing to its nonspecific or mild clinical features. In 20–35% of cases, sarcoidosis initially presents on skin. However, skin lesions commonly mimic dermatological conditions. Therefore, it is important to not underestimate the skin manifestations and perform histopathological examinations to make a timely diagnosis. Case presentation We present two cases of 33-year-old Caucasian female patients with orange–red macules and plaques that developed in the eyebrow area 1 and 6 years after microblading, respectively. Histopathological examination confirmed a diagnosis of sarcoidosis. The lymph nodes and lungs were also affected in both patients. Conclusion Our two reports suggest that an esthetic procedure involving dermal or subcutaneous injection of foreign materials can trigger the development of cutaneous and systemic sarcoidosis. However, this relationship has not been described yet. Physicians should, therefore, be aware of this complication to properly evaluate and treat such patients in a timely manner.

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16622 Granulomatous reaction to microneedling

Cited by 2 publications

References 0 publications

A case of a delayed granulomatous reaction on the face following microneedling: A case report

A case of a delayed granulomatous reaction on the face following microneedling: A case report

Microblading reaction as a manifestation of systemic sarcoidosis: two case reports and a review of the literature

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