160: Intralymphocytic Cyclosporine Exposure Is Not Accurately Predicted by C0 or C2 Blood Levels in Everolimus Treated Patients

Assessment of the Cylex ImmuKnow Cell Function Assay in Pediatric Heart Transplant Patients

“…This strategy likely provides only a gross assessment of immunologic activity. Moreover, cyclosporine troughs correlate poorly with the area under the curve concentration 9 and may not correlate with intralymphocytic concentration, 27 and thus may not accurately indicate patients at risk for AR, infection, or medication toxicities. As a consequence, additional tests are needed to indicate which patients are at risk.…”