155 Clinical, immunological and genetic findings in 22 patients with combined immunodeficiency treated in a specialized center in Croatia

Abstract

IgE is 268IU/ml. Specific IgE to Tomato-0.02, Strawberry-0.01, Kiwi fruit-0.03, . Thyroid function test, MRI brain were normal. Investigations performed for Wilson's disease, which were unremarkable. Coeliac screen was normal. Hereditary angioedema scree is normal There was no record of basal serum tryptase level. Treatment Initial diagnosis of idiopathic anaphylaxis made. Later with new neurological and eye symptoms, diagnosis of mast cell activation syndrome suspected, and he was started on trial of oral sodium cromoglycate capsules.In next clinic follow up, his symptoms were completely resolved and feedback from school was excellent in terms of concentration. Discussion Symptoms of allergic disorders are very wide. Mast cell activation syndrome especially with multisystem involvement should be a differential to Idiopathic Anaphylaxis.