Abstract:Introduction In severe aortic stenosis (AS) myocardial perfusion and myocardial strain (in particular longitudinal strain-LS) are reduced. Reduced myocardial perfusion in severe AS is thought to occur in the subendocardium due to increased LV pressure, leading to reduced LS and increased fibrosis. Our group previously showed a good correlation between pre-contrast T1 values using SHMOLLI (Shortened Modified Look-Locker Inversion recovery) sequence and histological quantification of diffuse fibrosis in severe A… Show more
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