15 Prevalence and characteristics of abnormalities on cardiac MRI in unselected patients after recovery from acute SARS-CoV-2 infection and correlation with markers of immunity and coagulation: the Study of HEarT DiseAse and ImmuNiTy After COVID-19 in Ireland (SETANTA)

Abstract

p=0.001). SAVR was an independent predictor of moderate-severe PPM (HR 1.80 95% CI 1.25-2.59, p=0.002) as was increased BMI (HR 1.14 per 1kg/m2 increase in BMI), pre-exiting hypertension (HR 2.09) and the use of smaller valve sizes (HR 29.06 for valve sizes 18-23mm). TAVR however was not a predictor of moderate-severe PPM. Inhospital mortality was 3.9% in TAVR versus 6.1% in SAVR group (p=0.171). Two-year outcomes including allcause and cardiovascular mortality, and readmissions were similar in both groups (log rank p>0.05 for all comparisons). Predictors of all-cause 2-year mortality differed between groups although low baseline haemoglobin and post procedure stage 2-3 acute kidney injury were predictors following both SAVR and TAVR. Moderate-severe PPM however, was a predictor of all-cause 2-year mortality after SAVR (HR 1.78; 95% CI 1.10-2.88, p=0.018), but not after TAVR (p=0.737). Conclusions SAVR and TAVR offer similar mid-term outcomes in MO patients with severe AS, however, TAVR offers advantages in terms of periprocedural morbidity and reduced incidence of moderate-severe patient prosthesis mismatch.