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Abstract

Calcium phosphate (CaP) coatings, from 40,000 to 200,000 nm thick, on titanium and titanium alloy substrates, were produced using radio frequency (RF) sputtering. Such coatings on dental implants have the potential for improving initial bone ingrowth rates. The success of these coatings may allow the movement from two stage implant systems to single stage implant systems, significantly reducing the time required for healing and fixture placement. Glass source materials were developed for the RF sputtering facility and the resultant coatings were characterized and compared to coatings sputtered from a conventional plasma sprayed hydroxyapatite (HA) source material. The coatings were characterized according to their chemistry, crystalline orientation, and residual strain.

Zeta potential measurement in bioactive collagen

“…SBF and blood plasma ion concentrations are given in Table I. A weight / volume solution ratio equal to 0.002 g/cm 3 was used for all samples tested. SBF immersion tests were made in triplicate.…”

“…An important group has the ability to react with living tissues and promote a real interaction with them 1,2 . This interaction occurs by means of a hydroxyapatite (HA) layer formed inductively by the implanted material 3,4 . Due to experimental difficulties to accomplish in vivo assays [5][6][7][8][9] , bioactivity was evaluated in a acellular medium which simulates in vivo conditions.…”

Slowly Delivered Icariin/Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical‐Size Bone Defects

“…The osseous repair of large-volume bone defects is still a challenge in the fields of orthopedics, maxillofacial surgery, and dental implantology. Although autologous bone grafts are routinely adopted to treat large-volume bone defects, the disadvantages of these grafts (e.g., limited quantity, donor site morbidity) have engendered tremendous efforts to develop alternatives [ 1 ], among which bone tissue engineering technique is highly promising [ 2 , 3 ]. Bone tissue engineering technique is an interdisciplinary science that applies the principles of biology and engineering to develop viable substitutes for restoring, maintaining, or improving the function of bone tissue.…”