(149) Factors associated with prescription opioid abuse in a cross-sectional cohort of new pain clinic patients

Zocca, Jennifer; Sharifzadeh, Yasamin; Mackey, Sean; Hah, Jennifer M.

doi:10.1016/j.jpain.2015.01.063

Cited by 1 publication

(2 citation statements)

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“…Furthermore, descriptive data such as those provided are limited in the literature, as many published studies have been limited to the assessment of sociodemographic factors associated with opioid misuse, abuse, and overdose. [33][34][35] The current analysis of population (as opposed to clinical) data extends our knowledge about the associations among sociodemographic, headache, and other characteristics associated with opioid use in those with migraine. Opioid use is generally associated with greater headache-related burden; markers of worse health, including elevated BMI and CV, and psychiatric comorbidities; elevated TPI and ED/UC facility use; and poorer quality of life.…”

Section: Continuedmentioning

confidence: 82%

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Characterizing opioid use in a US population with migraine

et al. 2020

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ObjectiveTo determine the prevalence of and risk factors associated with opioid use in the treatment of migraine, we examined demographics and clinical characteristics of 867 individuals who reported using opioids for the treatment of migraine.MethodsWe analyzed data from the CaMEO study (Chronic Migraine Epidemiology and Outcomes), a cross-sectional, longitudinal, Internet study, to compare sociodemographics, clinical characteristics, and migraine burden/disability of opioid users vs nonusers. Covariates were entered as categorical or continuous variables. Factors associated with opioid use were identified using nested, multivariable binary logistic regression models.ResultsOf 2,388 respondents with migraine using prescription medications for acute treatment, 36.3% reported that they currently used or kept on hand opioid medications to treat headaches. Current opioid users had significantly more comorbidities, greater headache-related burden, and poorer quality of life than nonusers. Regression models revealed factors significantly associated with opioid use, including male sex, body mass index, allodynia, increasing monthly headache frequency, Total Pain Index score (excluding head, face, neck/shoulder), anxiety, depression, ≥1 cardiovascular comorbidity, and emergency department/urgent care use for headache in the past 6 months. Self-reported physician-diagnosed migraine/chronic migraine was associated with significantly decreased likelihood of opioid use.ConclusionsOf respondents who were using acute prescription medications for migraine, more than one-third used or kept opioids on hand, contrary to guidance. This analysis could not distinguish risk factors from consequences of opioid use; thus further research is needed to guide the development of strategies for reducing the inappropriate use of opioids in migraine.

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Section: Continuedmentioning

confidence: 82%