148 Locally Acquired Hepatitis E. Geographical Clustering and Environmental Factors: A Nested Case Control Study

Hepatitis E: source and route of infection, clinical manifestations and new developments

“…Provisional data from Cornwall have confirmed these findings. In a case–control study, 50% of cases of autochthonous HEV were found to live within 2 km of the coast . The explanation for this observation is uncertain.…”

Neuralgic amyotrophy and hepatitis E virus infection

“…19,20 The reason for this observation is uncertain, but one possibility is that such patients become infected via recreational use of beach areas. 19,20 The reason for this observation is uncertain, but one possibility is that such patients become infected via recreational use of beach areas.…”

Hepatitis E: The ‘New Kid on the Block' or an Old Friend?

“…All the above are potential sources of human infection, and other ‘hiding places' of HEV are being actively sought. For example, in our large cohort of well-documented cases of locally acquired hepatitis E in Cornwall, UK, approximately 50% of cases live within 2 km of the coast [10]. The cause of such geographical coastal clustering is unknown, but one explanation is that some of these cases may be due to recreational use of contaminated beach areas and coastal waters.…”