Abstract:Moreover, only 1/4 RAD51-low/TIL-high tumors achieved pCR but none of them relapsed.
Conclusions:The RAD51 test is able to identify HRR-altered tumors, beyond gBRCA1/ 2 mutations, and to select a cohort of RAD51-low pts with better prognosis in a platinum-free neoCT setting. Biomarker analyses on treated paired tumors and on a larger cohort of pts are ongoing. Results will be available for the congress.Legal entity responsible for the study: The authors.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.