132-LB: A Randomized Controlled Trial Comparing Glargine U300 and Glargine U100 for the Inpatient Management of Medicine and Surgery Patients with Type 2 Diabetes: Glargine U300 Hospital Trial
Abstract:This prospective, open-label, randomized clinical trial compared the safety and efficacy of a basal bolus regimen using glargine U300 or glargine U100 for the management of general medicine and surgery patients with T2D. A total of 171 patients (age: 57±12 years, admission BG: 229±82 mg/dl and HbA1c: 9.5±2.2% [mean±SD]), treated with oral agents or insulin prior to admission, were randomized to glargine U300 (n=90) or glargine U100 (n=81). Total daily dose (TDD) started at 0.4 U/kg/d for BG: 140-200 mg/dl or 0… Show more
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