13-P043 Unraveling the complex mechanisms of spatial and temporal Sonic hedgehog expression in the limb

Abstract

intracellular signalling pathways in neuron-like cells and for their ability to stimulate neurite outgrowth of neuron-like cells.Milk proteins that have shown effects on neural-like cell lines are being tested in vitro using a whole gut culture system to examine their effects on the neonatal ENS development.Activin A/TGFb, FGF, Wnt and BMP signalling are crucial for the self-renewal and early differentiation of human embryonic stem cells (hESCs). However, the mechanism of how they coordinate to regulate these two processes is unclear. To address this ques-