Abstract:Background: Primary Epstein-Barr virus (EBV) infection frequently occurs early after transplantation (Tx) in seronegative pediatric heart Tx recipients who receive organs from seropositive donors and is the key risk factor for the development of post-transplant lymphoproliferative disorder (PTLD). The routine use of post-Tx EBV-PCR monitoring offers the opportunity to study the time course of primary EBV infection and the influence of differing immunosuppressive regimens. Methods: We studied 15 consecutive ser… Show more
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