Abstract:Introduction: Ulcerative colitis (UC) is an idiopathic, autoimmune, and inflammatory disorder which affects the lining of the colon and the rectum. It involves inflammatory mediators such as cytokines, nitrogen and oxygen-derived free radicals exerting oxidative stress, deranged colonic milieu, and increase in intestinal permeability. Ricinus communis roots are used traditionally in diseases of liver and rectum, in gastropathy such as constipation, inflammation, fever, colic and in colon cancer. Several report… Show more
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