2009
DOI: 10.1016/s0168-8278(09)60130-6
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128 Five Year Prospective Evaluation of Liver Histology in Patients With Chronic Hepatitis C Virus (Hcv) Following Treatment With Interferon/Peginterferon and Ribavirin (Ifntx)

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“…5,6 Patients who achieve an SVR have improvement in liver histologic features and regression of fibrosis. 7,8 Patients with cirrhosis who achieve an SVR rarely experience hepatic decompensation and have a 10-fold decrease in the risk of HCC and a significant reduction in mortality. [9][10][11] For the past 15 years, interferon and then peginterferon (PEGINF) have been the backbone of HCV treatment on which ribavirin (RBV) and more recently HCV protease inhibitors have been added.…”
mentioning
confidence: 99%
“…5,6 Patients who achieve an SVR have improvement in liver histologic features and regression of fibrosis. 7,8 Patients with cirrhosis who achieve an SVR rarely experience hepatic decompensation and have a 10-fold decrease in the risk of HCC and a significant reduction in mortality. [9][10][11] For the past 15 years, interferon and then peginterferon (PEGINF) have been the backbone of HCV treatment on which ribavirin (RBV) and more recently HCV protease inhibitors have been added.…”
mentioning
confidence: 99%