124 Low-Back Pain Relief With a New 32-Contact Surgical Lead and Neural Targeting Algorithm

Pilitsis, Julie G.; Barolat, Giancarlo; Rosenow, Joshua M.; Brennan, James J.; Bailey, Alexander; Epstein, Jeffrey M.; Hammond, Blake; Metzger, Clark; Huynh, Dat; Lechleiter, Kristen; Mekel-Bobrov, Nitzan

doi:10.1227/01.neu.0000489694.03538.88

Cited by 4 publications

(2 citation statements)

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“…The evolution of hardware and software for spinal cord stimulation in pain management has advanced ahead of that of DBS. Spinal cord stimulation hardware now includes surgical paddles with 32 contacts125, expanded MRI labelling, pulse generators with built-in accelerometers126, the ever-shrinking size of pulse generators, systems with no pulse generator127 and special leads for stimulation of the dorsal root ganglion. The field is also reaping the benefits of new waveforms and software strategies, such as high-frequency, high-density and burst stimulation.…”

Section: Emerging Technology and Strategiesmentioning

confidence: 99%

Deep brain stimulation: current challenges and future directions

et al. 2019

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The clinical use of deep brain stimulation (DBS) is among the most important advances in the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly measure pathological brain activity and can deliver adjustable stimulation for therapeutic effect in neurological and psychiatric disorders correlated with dysfunctional circuitry. The development of DBS has opened new opportunities to access and interrogate malfunctioning brain circuits and to test the therapeutic potential of regulating the output of these circuits in a broad range of disorders. Despite the success and rapid adoption of DBS, crucial questions remain, including which brain areas should be targeted and in which patients. This Review considers how DBS has facilitated advances in our understanding of how circuit malfunction can lead to brain disorders and outlines the key unmet challenges and future directions in the DBS field. Determining the next steps in DBS science will help to define the future role of this technology in the development of novel therapeutics for the most challenging disorders affecting the human brain.

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Section: Emerging Technology and Strategiesmentioning

confidence: 99%

Deep brain stimulation: current challenges and future directions

et al. 2019

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“…Evolutions in technologies have led to the advancement in pain management in DBS. Several technologies related to spinal cord stimulation like Expanded MRI labeling, pulse modifier (generator as well as shrinker), dorsal root ganglia stimulating leads, and so on have benefited a lot due to high-frequency and high-density strategies of software [82][83][84][85]. The major problem in DBS is the inappropriate dose, for which no new technology has been developed for the past two decades; therefore, there is lack of competitiveness in DBS technology [30].…”

Section: Evolution In Dbs Technologiesmentioning

confidence: 99%

Deep Brain Stimulation Approach in Neurological Diseases

Priya¹,

Abhishek²

2020

Neurostimulation and Neuromodulation in Contemporary Therapeutic Practice

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The technique was emanated in early 1960s; nowadays, deep brain stimulation (DBS) has become a huge practice in treatment of various movement disorders along with some psychiatric disorders. The advancement of DBS in different neurodegenerative diseases and managing patients with refractory brain disorders are closely related to the developments in technology. This development in regard with the device advancement along with the safe coupling of DBS to high-resolution imaging can help us to shape our knowledge in brain-wide networks and circuits linked with clinical aspects. DBS is found to be useful in learning and memory. On the contrary, traditional epilepsy surgeries are more complicated and technologically DBS is easier and more feasible. There are mild adverse effects of this DBS treatment, but a number of studies have shown positive treatment outcome with movement disorders and many kinds of psychiatric disorders too.

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New advancements in spinal cord stimulation for chronic pain management

Liu

Cheng

2017

Current Opinion in Anaesthesiology

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HF-10 SCS is free of paresthesia and associated with significantly better coverage of axial lower back pain. Burst stimulation invokes minimal paresthesia and provides better coverage of low back pain. DRG stimulation results in better outcomes in patients with complex regional pain syndrome. It requires less energy and delivers consistent stimulation regardless of postural variations. Clinical trials with new SCS modalities, such as Stimwaves, are under way to make SCS wireless. Intraoperative neuromonitoring and paresthesia atlas may be used to guide lead placement. Multicolumn surgical paddle leads enable a combination of independent current control with up to 32 contacts for better programming and better coverage.

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124 Low-Back Pain Relief With a New 32-Contact Surgical Lead and Neural Targeting Algorithm

Cited by 4 publications

References 0 publications

Deep brain stimulation: current challenges and future directions

Deep brain stimulation: current challenges and future directions

Deep Brain Stimulation Approach in Neurological Diseases

New advancements in spinal cord stimulation for chronic pain management

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