123I-mIBG: Simplicity and reproducibility

123I-MIBG cardiac sympathetic imaging provides further insight into cardiorenal interactions in systolic heart failure patients

“…The heart-to-mediastinal (H/M) ratio was derived from early and late activities and the wash out rate was calculated. 8,9 As it was observed, the GFR positively correlated with late H/M ratio (r = 0.215; p \ 0.001), signifying some interaction among reductions in kidney function and an impairment of cardiac sympathetic activity. When the study population was sub-grouped into moderate-to-severe and normal-tomild GFR reduction, a decrease in late H/M ratio was noted in patients with renal dysfunction compared to those without (1.49 ± 0.21 vs. 1.56 ± 0.26, p = 0.03).…”