“…[25] Others have reported brachial artery flow mediated dilation and pulsatility index change, bedside cardiovascular maternal interrogation in the first trimester, first trimester blood pressure and serum soluble fms-like tyrosine kinase-1, and placental growth factor as possible predictors of HDP. [26,27,28,29] Hypertensive disorders in pregnancy are a group of diseases that are clinically characterized by elevation of blood pressure with or without presence of protein in the urine in later half of pregnancy. They include GH, PE, chronic hypertension with superimposed PE, and eclampsia.…”