1152 Outcomes of Patients With T1B Esophageal Adenocarcinoma: A Multicenter Cohort Study

Endoscopic submucosal dissection: evolving role and position in the management of Barrett’s neoplasia

“…Previous surgical series have reported an increasing rate of LNM based on invasion depth (sm1 0–22 %, sm2/3 36 %–54 %). However, recent studies based on endoscopic resection data report substantially lower LNM rates for submucosal cancer (0–14 %) 3 4 . The risk of LNM compared with rates of surgical morbidity has so far dictated the management of T1b esophageal adenocarcinoma (EAC).…”

“…Conversely, T1b cancers are considered to be better managed with esophagectomy owing to the risk of lymph node metastasis (LNM). Surgery has also been shown to improve overall survival compared with EMR for T1b tumors 3 . While the risk of LNM with T1a cancer is negligible, favoring endoscopic resection due to its low risk of morbidity and mortality, the risk of LNM for T1b cancer is not clear.…”