114 Prognostic factors in follicular and huerthie cell carcinoma of the thyroid gland — A multivariate survival analysis

Bešič, Nikola; Žgajnar, Janez; Bergant, Damijan; Hočevar, Marko; Pompe, F.; Auersperg, M.; Grazio-Frkovic, Snjezana

doi:10.1016/s1359-6349(03)90147-9

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This could be a result of fewer patients in most studies, which means that small variations in the variables analyzed can lead to a prognostic factor being significant or not. As a general rule, the following prognostic factors have been reported for this type of carcinoma: age, tumor differentiation, vascular invasion, distant metastasis, nodular affectation, capsular invasion, and tumor extension (13,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37), although, as we have already mentioned, there is a great amount of variability between studies.…”

Section: Discussionmentioning

confidence: 83%

Are prognostic scoring systems of value in patients with follicular thyroid carcinoma?

Rı́os¹,

Rodrı́guez²,

Ferri

et al. 2013

European Journal of Endocrinology

View full text Add to dashboard Cite

Purpose: Most prognostic systems for differentiated carcinoma have been designed for papillary carcinoma. Objective: To analyze the value of the existing prognostic systems for evaluating follicular carcinoma and to determine whether any of them have a better predictive effect. Methods: A total of 66 follicular carcinomas were analyzed. The following prognostic systems were studied: EORTC, AGES, AMES, MACIS, TNM, and NTCTCS. Results: The AGES and AMES systems did not demonstrate a good prognostic correlation. In the EORTC system, the rate of disease-free patients was 89% in group 1, 75% in group 2, 69% in group 3, and 0% in group 4. The MACIS system showed 83, 60, 67, and 0% of disease-free patients respectively. The TNM system showed 81, 71, 50, and 0% of disease-free patients respectively. Finally, the NTCTCS system demonstrated 100, 84, 53, and 0% of disease-free patients respectively. Cox's regression analysis was used to calculate the proportion of variation in survival time explained (PVE). The prognostic classification system with the greatest survival prediction was EORTC at 67.64% of PVE, followed by TNM at 62.5% of PVE, and MACIS at 57.82% of PVE. Conclusions: MACIS and TNM are good prognostic systems for evaluating follicular thyroid carcinoma, although the one with the most prognostic value was the EORTC system.

show abstract