111 In-pentetreotide SPECT CT Value in Follow-up of Patients with Neuro-Endocrine Tumors

Al-Suqri, Badriya

doi:10.5001/omj.2014.95

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Diagnosis Imaging1

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2019

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“…55 Misinterpretation of physiological lymph node uptake may falsely upstage a patient's disease. 44,56…”

Section: Diagnosis Imagingmentioning

confidence: 99%

Management of Gastrointestinal Neuroendocrine Tumors

Wang

Zheng-Pywell

Chen

et al. 2019

Clin Med Insights Endocrinol Diabetes

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Neuroendocrine neoplasms (NENs) are derived from neuroendocrine cell system and can have benign or malignant characteristics. They are rare tumors, but have been increasing in incidence over the past 40 years. Patients with NENs may develop symptoms due to primary tumor invasion, metastasis, or from secretion of hormonally active tumor substances. Multiple imaging modalities are used for diagnosis and staging, including specialty scans such as 111In pentetreotide (Octreoscan) and 68Gallium-DOTATATE, along with endoscopy, endoscopic ultrasound, and biochemical marker testing. Treatment involves both surgical approach, for both primary and metastatic lesions, as well as medical management for symptom management and disease progression. This article will review the current clinical knowledge regarding the diagnosis, treatment, and prognosis of these fascinating neoplasms and the associated hormonal syndromes.

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“…55 Misinterpretation of physiological lymph node uptake may falsely upstage a patient's disease. 44,56…”

Section: Diagnosis Imagingmentioning

confidence: 99%