1092 5-alpha reductase inhibitors diminish the rate of progression in men with low risk prostate cancer on active surveillance

Finelli, Antonio; Trottier, Greg; Lawrentschuk, Nathan; Sowerby, Robert J.; Zlotta, Alexandre R.; Radomski, Lenny; Timilshina, Narhari; Evans, Alyson; Kwast, Theo H. van der; Toi, Ants; Jewett, Michael A.S.; Trachtenberg, John; Fleshner, Neil

doi:10.1016/s1569-9056(12)61088-4

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In einer allerdings retrospektiven Analyse von 288 Männern mit einem Lowrisk-Prostatakarzinom unter "active surveillance" ergaben sich für die Patienten, die wegen einer gleichzeitig bestehenden, symptomatischer Prostatavergrößerung mit Finasterid behandelt worden waren, signifikante Vorteile in Hinblick auf eine Progression in der Stanzbiopsie, die Notwendigkeit eines Therapiewechsels und die Zeit bis zur Progression [15].…”

Section: α-Reduktasehemmerunclassified

“…skelettbezogene Komplikationen eines metastasierten Tumors positiv beeinflussen kann [15,30,31]. Saad et al [25,26] konnten in ihrer kontrollierten, randomisierten Studie bei Patienten mit metastasiertem, kastrationsresistenten Prostatakarzinom eine signifikante Reduktion skelettbezogener Komplikationen, insbesondere auch von metastatischen Frakturen unter Gabe von Zoledronsäure nachweisen.…”

Section: Introductionunclassified

See 1 more Smart Citation

Sekundär- und Tertiärprävention urologischer Tumore

Schmitz‐Dräger

Lümmen

Bismarck

et al. 2011

Urologe

View full text Add to dashboard Cite

The amount and quality of available data on secondary and tertiary prevention of urological tumors are to a large extent unsatisfactory. In the areas of nutrition and supplementary diet the consumption of tomatoes and especially tomato products could have a beneficial effect on the course of the disease for patients with prostate cancer, whereas there is evidence that the consumption of foodstuffs containing calcium (milk and milk products) and linolenic acid as well as a fat-rich diet accelerate tumor progression. Despite as yet unsatisfactory data, men with urothelial tumors or prostate cancer should abstain from smoking and undertake sports activities. For medicinal measures the administration of 5-alpha-reductase inhibitors and bone-promoting substances for patients with prostate cancer are under discussion. The effectiveness of the substances zoledronate and denosumab has been demonstrated in prospective randomized studies. The authors recommend that the scientifically neglected field of tertiary prevention of urological tumors should in future be included as a core factor of scientific investigations.

show abstract

Section: α-Reduktasehemmerunclassified