Abstract:Background Autoimmune encephalitis is an increasingly recognised disease that presents with seizures, neuropsychiatric symptoms, dystonic movements, and autonomic dysfunction 1 . As the mainstay of treatment immunosuppressive therapies are most effective when subject to early initiation and timely escalation, both of which are recognised to affect outcomes 2 . Nevertheless approximately half of patients with NMDA-R antibody encephalitis do not respond adequately to first-line therapy, and a significant proport… Show more
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