100Potentially Inappropriate Prescribing of Proton Pump Inhibitors – A Qualitative Study

McMahon, Niamh; McGowan, Aisling; Melanophy, Gail; Henman, Martin

doi:10.1093/ageing/afx144.117

Cited by 1 publication

(1 citation statement)

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“…However, physicians’ and patients’ awareness regarding this issue remains poor. In a survey on 120 elderly patients, the majority of the participants were not familiar with any reports linking long-term proton pump inhibitor use with adverse effects, reported no concerns related to their chronic use, and stated that they had not discussed the benefits and risks of this therapy with their primary care providers [ 40 , 41 ]. It is also to be acknowledged that older adults often report feeling uncomfortable discussing whether to stop proton pump inhibitors with their providers [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Potentially Inappropriate Prescribing among Elderly Outpatients: Evaluation of Temporal Trends 2012–2018 in Piedmont, Italy

Galimberti

Casula

Scotti

et al. 2022

IJERPH

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Pharmacological intervention is one of the cornerstones in the treatment and prevention of disease in modern healthcare. However, a large number of drugs are often prescribed and used inappropriately, especially in elderly patients. We aimed at investigating the annual prevalence of potentially inappropriate prescriptions (PIPs) among older outpatients using administrative healthcare databases of the Piedmont Region (Italy) over a seven-year period (2012–2018). We included all Piedmont outpatients aged 65 years or older with at least one drug prescription per year. Polypharmacy and the prevalence of PIPs according to the ERD list explicit tool were measured on an annual basis. A range between 976,398 (in 2012) and 1,066,389 (in 2018) elderly were evaluated. Among them, the number of subjects with at least one PIP decreased from 418,537 in 2012 to 339,764 in 2018; the prevalence significantly reduced by ~25% over the study period. The stratified analyses by age groups and sex also confirmed the downward trend and identified several differences in the most prevalent inappropriately prescribed drugs. Overall, despite a reduction in PIP prevalence, one out of three older outpatients was still exposed to inappropriateness, highlighting the extensive need for intervention to improve prescribing.

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Section: Discussionmentioning

confidence: 99%