1000 cSt silicone oil vs heavy silicone oil as intraocular tamponade in retinal detachment associated to myopic macular hole

Mete, Maurizio; Parolini, Barbara; Maggio, Emilia; Pertile, Grazia

doi:10.1007/s00417-010-1557-9

Cited by 35 publications

(29 citation statements)

References 29 publications

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“…The drawback of silicone oil is that, due to its toxicity and elevation of intraocular pressure, it will have to be removed in most patients, requiring a new surgical procedure with its potential complications. Mete et al [45] found similar results in terms of visual gain and retinal reapplication for both 1,000 cSt silicone oil and heavy silicone oil, retrospectively.…”

Section: Macular Hole Retinal Detachmentsupporting

confidence: 74%

Myopic Traction Maculopathy

Gómez-Resa

Burés-Jelstrup²,

Mateo³

2014

Microincision Vitrectomy Surgery

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Myopic traction maculopathy is a high myopia-related complication caused by several mechanisms with traction as a common pathway. Macular hole-related retinal detachment is considered to be the final stage of progressive foveoschisis. In this setting, release of all vitreous and epiretinal tractions is essential in order to achieve surgical success. Pars plana vitrectomy has proven useful in the treatment of myopic foveoschisis, with both good visual and anatomical results. However, the surgical technique for the treatment of macular hole-related retinal detachment is still a controversial issue: reoperations are common and the final visual prognosis is limited, especially in those cases with a pronounced posterior staphyloma. We must also bear in mind that a highly myopic eye has some characteristic traits that may complicate vitreoretinal surgery. In these cases, microincision vitrectomy surgery may offer some advantages compared to conventional vitrectomy.

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Section: Macular Hole Retinal Detachmentsupporting

confidence: 74%

Myopic Traction Maculopathy

Gómez-Resa

Burés-Jelstrup²,

Mateo³

2014

Microincision Vitrectomy Surgery

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“…This discrepancy is likely to be related to the limited elasticity of the retina, which should be stretched to cover the staphyloma [1]. Therefore, an elevated/open or flat/open MH shape has been frequently reported after surgery for MMH after vitrectomy and ILM peeling [29–32].…”

Section: Discussionmentioning

confidence: 99%

Inverted ILM Flap for the Treatment of Myopic Macular Holes: Healing Processes and Morphological Changes in Comparison with Complete ILM Removal

Mete

Alfano

Maggio

et al. 2019

Journal of Ophthalmology

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Purpose. To investigate the microstructural changes after successful myopic macular hole (MMH) surgery, comparing inverted ILM flap and complete ILM removal techniques, and their association with visual function. Methods. Spectral-domain optical coherence tomography (SD-OCT) was used to evaluate both external limiting membrane (ELM) and ellipsoid zone (EZ) recovery in 40 eyes of 39 patients who underwent pars plana vitrectomy with either inverted internal limiting membrane flap technique (n=27) or complete ILM removal (n=13) to achieve MH closure. The association between ELM and EZ recovery and visual acuity was also investigated. The patients were followed up at 1 year. Results. ELM and EZ was recovered in 72% and 62% of cases, respectively, regardless of the surgical techniques 1 year after surgery. A strong positive association between the ELM and EZ recovery and the mean BCVA was found: regardless of the surgical technique, this was statistically significant at each time point (p<0.05). None of the baseline variables were found to act as predictive factors for either ELM or EZ. Conclusion. The inverted ILM flap technique did not affect the MMH healing processes compared to complete ILM removal. Thus, the presence of the ILM plug did not interfere with the restoration of both ELM and EZ, which correlated with functional recovery.

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“…No statistically significant differences were found between the two groups ( P = 0.238, Fisher's exact test). [ 20 ] Romano et al . stated that the long-term increased IOP depends on an open-angle mechanism rather than a closed-angle mechanism, since they did not report any case of pupillary block associated with SSO or HSO.…”

Section: Discussionmentioning

confidence: 99%

“…[ 13 14 15 ] The OH represents an important risk factor for both SSO and HSO, which can lead to the development of secondary glaucoma. [ 16 17 ] To clarify, if this complication was associated to the type of SO, several studies have been conducted,[ 18 19 20 21 22 ] nevertheless they have reduced statistical power and discordant results. Therefore, a systematic review was needed to clarify this issue.…”

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confidence: 99%

Development of ocular hypertension secondary to tamponade with light versus heavy silicone oil: A systematic review

Romano

Cruciani²,

Semeraro

et al. 2015

Indian J Ophthalmol

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Aim:The intraocular silicone oil (SO) tamponades used in the treatment of retinal detachment (RD) have been associated with a difference ocular hypertension (OH) rate. To clarify, if this complication was associated to use of standard SO (SSO) versus heavy SO (HSO), we performed a systematic review and meta-analysis of comparative study between two kind of SO (standard or light vs. heavy) for the treatment of RD and macular hole, without restriction to study design.Materials and Methods:The methodological quality of two randomized clinical trials (RCTs) were evaluated using the criteria given in the Cochrane Handbook for Systematic Reviews of Intervention, while three non-RCTs were assessed with the Newcastle-Ottawa Scale and Strengthening the Reporting of Observational Studies in Epidemiology checklists. We calculated Mantel-Haenszel risk ratio (RR) with 95% confidence intervals (95% CIs). The primary outcome was the rate of patients with OH treated with SSO compared to HSO.Results:There were a higher number of rates of OH in HSO compared to SSO. This difference was statistically significant with the fixed effect model (Mantel-Haenszel RR; 1.55; 95% CI, 1.06–2.28; P = 0.02) while there was not significative difference with the random effect model (Mantel-Haenszel RR; 1.51; 95% CI, 0.98–2.33; P = 0.06).Conclusion:We noted a trend that points out a higher OH rate in HSO group compared to SSO, but this finding, due to the small size and variable design of studies, needs to be confirmed in well-designed and large size RCTs.

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1000 cSt silicone oil vs heavy silicone oil as intraocular tamponade in retinal detachment associated to myopic macular hole

Abstract: PPV with ILM peeling and long-term tamponade was demonstrated to be a good surgical option to treat RD due to MMH; SO and HSO seemed to be equally effective, although the success rates remained far from an ideal 100%.

Cited by 35 publications

References 29 publications

Myopic Traction Maculopathy

Myopic Traction Maculopathy

Inverted ILM Flap for the Treatment of Myopic Macular Holes: Healing Processes and Morphological Changes in Comparison with Complete ILM Removal

Development of ocular hypertension secondary to tamponade with light versus heavy silicone oil: A systematic review

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