2014
DOI: 10.7162/s1809-48722012000100003
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What are the audiometric frequencies affected are the responsible for the hearing complaint in the hearing loss for ototoxicity after the oncological treatment?

Abstract: What are the audiometric frequencies affected are the responsible for the hearing complaint in the hearing loss for ototoxicity after the oncological treatment?Quais as frequências audiométricas acometidas são responsáveis pela queixa auditiva nas disacusias por ototoxicidade após o tratamento oncológico?

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Cited by 3 publications
(3 citation statements)
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“…At the base of the cochlea there are short and rigid fibers which are responsive to high frequencies, while at the apex these fibers are long and flexible, responding to the presence of low frequencies (22) . Studies show that ototoxic agents compromise high frequencies before low frequencies, due to the anatomical configuration (23) . Findings in the evoked otoacoustic emissions in individuals with hearing thresholds within the normal criteria are approximately 98%, disagreeing with the findings in this study, where even individuals in the lowest exposure group showed normal responses 48.1% of the time for TEOAE and 46.3% for DPOAE.…”
Section: Discussionmentioning
confidence: 99%
“…At the base of the cochlea there are short and rigid fibers which are responsive to high frequencies, while at the apex these fibers are long and flexible, responding to the presence of low frequencies (22) . Studies show that ototoxic agents compromise high frequencies before low frequencies, due to the anatomical configuration (23) . Findings in the evoked otoacoustic emissions in individuals with hearing thresholds within the normal criteria are approximately 98%, disagreeing with the findings in this study, where even individuals in the lowest exposure group showed normal responses 48.1% of the time for TEOAE and 46.3% for DPOAE.…”
Section: Discussionmentioning
confidence: 99%
“…This indicates the importance of high frequencies (6 and 8 kHz), which were not tested in our study due to the limitation of the equipment used. There is a consensus among researchers (5,7,19) that the auditory alterations caused by the use of ototoxic drugs initially involve high frequencies; hence, it is important to use equipment that can attain these frequencies.…”
Section: Discussionmentioning
confidence: 99%
“…One such change is ototoxicity, which is defined as the reaction that produces structural lesions in the inner ear, leading to irreversible sensorineural, descending, and bilateral auditory alterations (4) . These alterations initially involve the basal portion of the cochlea, affecting high frequencies, and may progress towards the cochlear apex, affecting middle and low frequencies (5) . Approximately 200 drugs are considered ototoxic, including polyfunctional alkylating agents, antimetabolites, antitumor antibiotics and mitotic inhibitors (6) .…”
Section: Introductionmentioning
confidence: 99%