Prognostic and Clinicopathological Value of ZWINT Expression Levels in Patients with Lung Adenocarcinoma: A Systematic Review and Meta-analysis

Evaluation of hypermetabolic mediastinal-hilar lymph nodes determined by PET/CT with EBUS-TBNA and calculation of SUVmax cutoff values in differentiation of malignancy

“…[7,11] Although adenocarcinoma is mostly located peripherally as a primary tumor, its prevalence is high among malignancies in the community. [12] The high incidence of adenocarcinoma diagnosis among malignancies in our study group is thought to be related to the prevalence of lung adenocarcinoma in the community. In addition, although adenocarcinoma is mostly a peripheral tumor, it can metastasize to mediastinal and hilar lymph nodes and tumors can be seen in more than 1 metastatic focus in the lung parenchyma.…”

“…Therefore, the diagnosis can be made from lymph node metastasis or an accessible metastatic nodule. [12][13][14] In our study, when the data of 94 lymph nodes were evaluated which were reported as negative as malignancy in the pathology result of the biopsy taken with EBUS-TBNA; 7 lymph nodes (7.5%) were found to be malignant after further examination with surgical biopsy and 21 lymph nodes (22.3%) were found to be malignant in the EBUS-TBNA/ percutaneous transthoracic aspiration biopsy/bronchoscopic biopsy performed simultaneously from another station or due to a known malignancy diagnosis. In our study, a total of 28 lymph nodes (29.8%) whose EBUS-TBNA result was initially negative for malignancy were then evaluated as malignant.…”

“…Therefore, the diagnosis can be made from lymph node metastasis or an accessible metastatic nodule. [12–14]…”