Multicomponent physical activity program to prevent body changes and metabolic disturbances associated with antiretroviral therapy and improve quality of life of people living with HIV: a pragmatic trial

Santos, Elisabete Cristina Morandi dos; Florindo, Alex Antônio; Santos, Ardiles Vitor; Picone, Camila de Melo; Dias, Tulio Gamio; Segurado, Aluísio Cotrim

doi:10.6061/clinics/2021/e2457

Cited by 1 publication

(1 citation statement)

References 28 publications

(37 reference statements)

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“…From June 2014 to May 2016 and from December 2017 to March 2018 we recruited PLH aged 18 to 59 years old who had started ART at the clinic for no longer than 4 months. The first recruitment period coincided with patient selection for a randomized pragmatic trial that investigated the impact of a multicomponent PA program to prevent body changes and metabolic disturbances associated with ART [17], whereas the second period initiated after the trial was completed. We excluded pregnant women, men and women with waist circumferences exceeding 102 cm or 88 cm, respectively; patients with comorbidities (diabetes mellitus, uncontrolled hypertension, stroke or cancer) or metabolic abnormalities (fasting blood glucose concentrations >100 mg/dL, total cholesterol >239 mg/dL, LDL-cholesterol >160 mg/dL, triglyceride >150 mg/dL); patients using anabolic steroids, hypolipidemic or hypoglycemic medication; those who reported esthetic surgery in the prior 12 months and those with contraindications for PA, such as severe immunosuppression or musculoskeletal disorders.…”

Section: Patient Selectionmentioning

confidence: 99%

Incorporating physical activity in the comprehensive care of people living with HIV starting antiretroviral therapy: Insights from a specialized care setting in São Paulo, Brazil

Santos

Picone

et al. 2021

PLoS ONE

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Background Managing HIV infection as a chronic condition includes encouraging adoption of healthy behaviors and promotion of physical activity (PA). However, people living with HIV (PLH) are often under social and programmatic vulnerability that may compromise behavior change. Understanding such barriers is crucial for successful incorporation of PA in their comprehensive care. Methods and findings In this study, we describe PA, energy intake from diet, and anthropometry of a cohort of PLH starting antiretroviral therapy (ART) at a Brazilian reference clinic, report how PA was addressed in routine care and investigate association between PA, energy intake and psychosocial constructs that may facilitate PA (social support and self-efficacy for PA). Among 61 PLH (86.9% males, mean age = 32.5 years) anthropometry was normal, but 47.5% reported PA below recommendations. Despite presenting high social support scores, family encouragement for PA was low, and self-efficacy classified as medium. Chart reviews yielded infrequent reports concerning PA. After adjusting for gender and age, we found a negative association between energy intake from diet and self-efficacy, but none between PA and energy intake or between PA and psychosocial constructs. Conclusions We conclude that patients in our cohort were insufficiently active when starting ART, and that PA was poorly addressed by caretakers in routine HIV care. Nevertheless, social support and self-efficacy scores suggest potential for behavioral change. Caregivers should therefore start considering patients’ vulnerabilities and establishing strategies to help them overcome barriers to incorporate PA in their comprehensive care effectively.

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Section: Patient Selectionmentioning

confidence: 99%