Neonatal SARS-CoV-2 infection

Carvalho, Werther Brunow de; Gibelli, Maria Augusta Bento Cicaroni; Krebs, Vera Lúcia Jornada; Calil, Valdenise Martins Laurindo Tuma; Nicolau, Carla Marques; Johnston, Cíntia

doi:10.6061/clinics/2020/e1996

Cited by 9 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, this systematic review comprised data from 236 newborns. Table S1 summarizes the data of the 72 included studies ( 13 , 14 , 15 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , ...…”

Section: Resultsmentioning

confidence: 99%

COVID-19 in Neonates with Positive RT–PCR Test. Systematic Review

García

Allende-López

Morales-Ruíz

et al. 2022

Archives of Medical Research

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

COVID-19 in Neonates with Positive RT–PCR Test. Systematic Review

García

Allende-López

Morales-Ruíz

et al. 2022

Archives of Medical Research

View full text Add to dashboard Cite

“…12 The infant was asymptomatic and there were no complications at birth. 62,63,[80][81][82][83][84][85][86][87] Negative cases 4,68,79,81,88-103 Mix-feeding 3 7 10 Positive cases [104][105][106] Negative cases 107 Not reported feeding practice 76 596 672 Positive cases 63,67, Negative cases 5,10,47,75,111,114,119,120,122, Positive cases 83,193,199,200 Mix-feeding 3 0 3 Positive cases 193,201 Not reported e feeding practice 125 2 127…”

Section: Participantsmentioning

confidence: 99%

Transmission of SARS‐CoV‐2 through breast milk and breastfeeding: a living systematic review

Centeno‐Tablante

Medina‐Rivera

Finkelstein

et al. 2020

Annals of the New York Academy of Sciences

139

123

View full text Add to dashboard Cite

The pandemic of coronavirus disease 2019 (COVID-19) is caused by infection with a novel coronavirus strain, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At present, there is limited information on potential transmission of the infection from mother to child, particularly through breast milk and breastfeeding. Here, we provide a living systematic review to capture information that might necessitate changes in the guidance on breast milk and breastfeeding given the uncertainty in this area. Our search retrieved 19,414 total records; 605 were considered for full-text eligibility and no ongoing trials were identified. Our review includes 340 records, 37 with breast milk samples and 303 without. The 37 articles with analyzed breast milk samples reported on 77 mothers who were breastfeeding their children; among them, 19 of 77 children were confirmed COVID-19 cases based on RT-PCR assays, including 14 neonates and five older infants. Nine of the 68 analyzed breast milk samples from mothers with COVID-19 were positive for SARS-CoV-2 RNA; of the exposed infants, four were positive and two were negative for COVID-19. Currently, there is no evidence of SARS-CoV-2 transmission through breast milk. Studies are needed with longer follow-up periods that collect data on infant feeding practices and on viral presence in breast milk.

show abstract

“…However, long-COVID may well be an under-recognized phenomenon [18]. The challenge of recognizing the clinical characteristics of COVID-19 among other neonatal diseases is apparent [19]. Some recognized manifestations of SARS-CoV-2 infection in children include stroke [20], seizures or seizure-like activities [21][22][23], headaches [21], dizziness [21], meningoencephalitis [21,[24][25][26],…”

Section: Discussionmentioning

confidence: 99%

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in children has been associated with a multisystem inflammatory syndrome and coronavirus disease 2019 (COVID- 19), and these are recognized as two different clinical entities [1][2][3]. It is widely known that, overall, a smaller proportion of children become ill when infected with SARS-CoV-2 compared to adults [4].…”

Section: Introductionmentioning

confidence: 99%

Coronavirus infection in neonates: Neurodevelopmental outcomes at 18 months of age

Ayed¹,

Alsaffar

Bahzad

et al. 2022

Preprint

View full text Add to dashboard Cite

Background: Although most neonates with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections have mild disease, the impact on neurodevelopmental outcomes is unknown. This study aimed to assess 18-month neurodevelopmental outcomes of neonates infected with SARS-CoV-2 infection. Methods: We conducted a prospective cohort study of neonates diagnosed with SARS-CoV-2 infection between June to August 2020 through nasopharyngeal coronavirus disease 2019 (COVID-19) PCR testing. A total of 58 neonates were identified from the Kuwait national COVID-19 registry and were enrolled. Historical controls were selected from the neonatal follow-up registry and matched 2:1 based on sex and gestational age. At 18 months of age, neurodevelopmental outcomes were assessed using Bayley Scales of Infant and Toddler Development-3rd Edition (BSID-III) by two trained assessors. Results: A total of 40 children were diagnosed with SARS-CoV-2 infection and included in the final analysis. The median age at infection was 18 days (range: 10-26 days). Eighteen (45%) were asymptomatic, 15 (37.5%) had a sepsis-like presentation, 5 (12.5%) had respiratory distress and 2 (5%) had a multisystem inflammatory syndrome in children (MIS-C)-like presentation. At 18 months follow up, only one child had severe developmental delay, and one child had a language delay. BSID-III outcomes did not significantly differ between the SARS-CoV-2 infected group and the control group. Conclusions: There is no difference in neurodevelopmental outcomes in children infected with SARS-CoV-2 infection at 18 months compared to controls, although longer neurodevelopmental follow-up studies are required.

show abstract

Neonatal SARS-CoV-2 infection

Cited by 9 publications

References 11 publications

COVID-19 in Neonates with Positive RT–PCR Test. Systematic Review

COVID-19 in Neonates with Positive RT–PCR Test. Systematic Review

Transmission of SARS‐CoV‐2 through breast milk and breastfeeding: a living systematic review

Coronavirus infection in neonates: Neurodevelopmental outcomes at 18 months of age

Contact Info

Product

Resources

About