Periradicular lesions in HIV-infected patients attending the faculty of dentistry: clinical findings, socio-demographics status, habits and laboratory data - seeking an association

Abstract

OBJECTIVE:The purpose of this study was to estimate the prevalence of periradicular lesions in HIV-infected Brazilian patients and to assess the correlation of several factors with the periradicular status.METHOD:One hundred full-mouth periapical radiographs were evaluated. A total of 2,214 teeth were evaluated for the presence of periradicular lesions, caries lesions, coronal restorations, pulp cavity exposure and endodontic treatment.RESULTS:The prevalence of periradicular lesions was 46%. There were no significant differences between individuals with or without periradicular lesions with respect to their socio-demographic status, habits, laboratory data and route of HIV infection. However, the presence of a periradicular lesion was statistically correlated with the number of teeth with endodontic treatment (p = 0.018), inadequate endodontic treatment (p = 0.025), images suggesting pulp cavity exposure (p = 0.002) and caries lesions (p = 0.001).CONCLUSIONS:The prevalence of periradicular lesions in HIV-infected individuals was 46% and was not related to HIV infection.

Expression of Inflammatory Markers RANK, MMP-9 and PTHrP in Chronic Apical Periodontitis from People Living with HIV Undergoing Antiretroviral Therapy

“…In PLWHIV, there is a reduced ability to respond immunologically to microbial aggression [ 9 ], and thus, the evolution of an endodontic infection may develop in a different manner. However, some authors have found no discrepancy in the prognosis of endodontic treatment in these patients [ 21 , 27 ], while others have observed changes in the periapical inflammatory exudate or even in the complexity of the bacterial communities within the root canal [ 28 , 29 ].…”