Attention deficit disorder/hyperactivity: a scientific overview

Polanczyk, Guilherme; Casella, Erasmo Barbante; Miguel, Eurí­pedes Constantino; Reed, Umbertina Conti

doi:10.6061/clinics/2012(10)01

Cited by 9 publications

(7 citation statements)

References 17 publications

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“…Some EF difficulties reported by ADHD patients are problems with deadlines and financial life, instability of motivation, difficultly regulating emotions, losing enthusiasm, not completing tasks, low frustration tolerance, and lack of self-monitoring -in addition to difficulties with taking initiative and starting tasks, inhibiting stimuli, planning, organizing and establishing priorities, setting goals, and time management 9 . Although pharmacological treatment in ADHD has proved effective 10 , some specific interventions could be planned to address specific EF deficits. These could be implemented in support of the pharmacological treatment and could help improve day-to-day patient functioning.…”

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confidence: 99%

Intervention for executive functions in attention deficit and hyperactivity disorder

Menezes

Dias

Trevisan

et al. 2015

Arq. Neuro-Psiquiatr.

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This study aimed to investigate if an executive functions (EF) intervention could promote these skills in individuals with attention deficit and hyperactivity disorder (ADHD). Eighteen children and adolescents, 7-13 years old, divided into experimental (EG, N = 8) and control (CG, N = 10) groups, were assessed in the Block Design and Vocabulary subtests of the WISC III and seven tests of EF. Parents answered two scales, measuring EF and inattention and hyperactivity signs. EG children participated in a program to promote EF in twice-weekly group sessions of one hour each. After 8 months of intervention, groups were assessed again. ANCOVA, controlling for age, intelligence quotient and pretest performance, revealed gains in attention/inhibition and auditory working memory measures for the EG. No effect was found for scales or measures of more complex EF. Results are not conclusive, but they illustrate some promising data about EF interventions in children and adolescents with ADHD.Keywords: regulation, intervention, executive function, inattention. RESUMOEste estudo investigou se uma intervenção para funções executivas (FE) pode promover essas habilidades em indivíduos com transtorno do déficit de atenção e hiperatividade (TDAH). Participaram 18 crianças e adolescentes, 7-13 anos, divididos em Grupo Experimental (GE, N = 8) e Controle (GC, N = 10), avaliados nos subtestes Blocos e Vocabulário do WISC III e sete testes de FE. Pais responderam a duas escalas mensurando FE e sintomas de desatenção e hiperatividade. As crianças do GE participaram de um programa de promoção de FE, em sessões de grupo de uma hora cada, duas vezes por semana. Após intervenção de oito meses, os grupos foram reavaliados. ANCOVA, controlando idade, QI e desempenho no pré-teste, revelou ganhos da intervenção em medidas de atenção/inibição e memória de trabalho auditiva para o GE. Nenhum efeito foi encontrado para as escalas ou medidas de FE mais complexas. Os resultados não são conclusivos, mas ilustram tendências promissoras sobre intervenções em FE em crianças e adolescentes com TDAH.Palavras-chave: regulação, intervenção, função executiva, desatenção.Attention deficit hyperactivity disorder (ADHD) is a developmental disorder that tends to persist for many years or entire lives. It is characterized as a persistent pattern of inattention and/or hyperactivity/impulsivity that is more frequent and severe than is typically observed in individuals at a comparable level of development 1 . Studies have sought to understand possible impairments associated with ADHD symptoms, which can be useful for the diagnosis of the disorder and for rehabilitation of deficit areas. In this sense, important neuropsychological processes have been implicated in ADHD, including executive functions (EF) 2 . EF are responsible for top-down control of cognition, behaviors, and emotions. Core EF include inhibition (the ability to control an automatic or prepotent response and to control one's attention and thoughts), flexibility (the capacity to change the foc...

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confidence: 99%

Intervention for executive functions in attention deficit and hyperactivity disorder

Menezes

Dias

Trevisan

et al. 2015

Arq. Neuro-Psiquiatr.

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“…Erythropoietin (Epo) is an acidic glycoprotein hormone that is produced by the kidney and to a much lesser degree (< 10 percent) the liver. Epo binds to transmembrane erythropoietin receptor (EpoR), which are expressed primarily by hematopoietic progenitor cells but also by nonhematopoietic cells and tissues such as endothelial cells, cardiomyocytes, and neurons, the liver, uterus, and retina [ 9 ]. It was showed that Epo has a neuroprotective and neurotrophic effects in animal models.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Performance of Erythropoietin and Erythropoietin Receptors Levels in Children with Attention Deficit Hyperactivity Disorder

Güngör

Kurutaş

Öner

et al. 2021

Clin Psychopharmacol Neurosci

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Objective: Attention deficit hyperactivity disorder (ADHD) is a heterogeneous, highly heritable, a common childhood neurobehavioural disorder resulting from complex gene-gene and gene-environment interactions. The erythropoietin (Epo)/erythropoietin receptors (EpoR) system turned out to have additional important functions in nonhematopoietic tissue. In this study, we aimed to investigate the levels of Epo and and EpoR, and also their diagnostic values in children with ADHD. Methods: A total of 70 children were included in the study, 35 drug-naive patients with ADHD (age: 6−12 years; male/female: 20/15) and 35 healthy controls (age: 6−12 years; male/female: 22/13). Serum Epo and EpoR levels was determined using a commercial sandwich enzyme-linked immunosorbent assay kit. Results: The results indicated that the levels of Epo decreased in patients with ADHD compared to control (p ＜ 0.05). On the other hand, EpoR levels increased in these patients (p ＜ 0.05). Furthermore, the ratio of Epo/EpoR was significantly lower in ADHD patients than controls (p ＜ 0.05). Receiver operator characteristic curve analysis showed high diagnostic performance for Epo and EpoR, areas under curve were 0.980 and 1.000, respectively. Conclusion: This is the first report to investigate the association between serum Epo and EpoR levels in ADHD patients. Our results indicated that Epo may play a role in the etiology of ADHD, and Epo therapy may be beneficial in these disorders if given in addition to the routine treatment of children with ADHD. Furthermore, our results reveal possible diagnostic value of Epo and EpoR.

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“…Tiene 3 tipos: inatención, hiperactividad, impulsividad. Puede tener muchas consecuencias como: embarazos precoces, baja autoestima, accidentes de tránsito, deserción escolar (3).…”

Section: Introductionunclassified

Trastorno por déficit de atención/hiperactividad

Villalobos¹

2019

Rev.méd.sinerg.

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El trastorno por déficit de atención/ hiperactividad (TDAH) es una enfermedad que afecta tanto a niños, adolescentes y adultos en todo el mundo, la cual ha sido mal diagnosticada por la dificultad de realizarlo, no se cuentan con exámenes de gabinete para esto, lo cual lo hace aun mas difícil. Presenta una etiología multifactorial y se presenta con mucha frecuencia junto con otros trastornos psiquiátricos. Lo cual afecta de forma importante la vida del paciente, lo cual hace primordial su estudio.

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Attention deficit disorder/hyperactivity: a scientific overview

Cited by 9 publications

References 17 publications

Intervention for executive functions in attention deficit and hyperactivity disorder

Intervention for executive functions in attention deficit and hyperactivity disorder

Diagnostic Performance of Erythropoietin and Erythropoietin Receptors Levels in Children with Attention Deficit Hyperactivity Disorder

Trastorno por déficit de atención/hiperactividad

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