Prolonged PR Interval and Outcome in Cardiac Resynchronization Therapy

Kewcharoen, Jakrin; Kanitsoraphan, Chanavuth

doi:10.5935/abc.20190101

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…A few single-centre studies and two post-hoc analyses of large RCTs (COMPANION and MADIT-CRT) indicated a potential benefit of implanting CRT in this patient subgroup. 244,279,280 In MADIT-CRT, the subgroup of non-LBBB patients who had a prolonged PR did benefit from CRT-D, with a 73% reduction in the risk of HF or death and an 81% reduction in the risk of all-cause mortality compared with ICD-only therapy. 279 In non LBBB patients with normal PR, CRT-D was associated with a trend towards an increased risk of HF or death and a >2-fold higher mortality compared with ICD therapy, suggesting a bidirectional significant interaction.…”

Section: Indication For Cardiac Resynchronization Therapy: Patients I...mentioning

confidence: 99%

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)

Glikson¹,

Nielsen²,

Kronborg³

et al. 2022

Revista Española de Cardiología (English Edition)

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Section: Indication For Cardiac Resynchronization Therapy: Patients I...mentioning

confidence: 99%

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)

Glikson¹,

Nielsen²,

Kronborg³

et al. 2022

Revista Española de Cardiología (English Edition)

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“…The P-R interval of more than 200 milliseconds is considered prolonged on the ECG [ 1 ]. Prolonged P-R interval might have a positive correlation with cardiovascular outcome [ 2 ]. The results of a study showed in the case of coronary artery disease (CAD) prolonged P-R interval is associated with adverse clinical outcomes including hospitalization following heart failure and death [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Can prolonged P-R interval predict clinical outcomes in non-ST elevation acute coronary syndrome patients?

Zareei,

Zareiamand,

Kamali

et al. 2024

BMC Cardiovasc Disord

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Background The present study aimed to respond to clinical question, can prolonged P-R interval predict clinical outcomes in non-ST elevation acute coronary syndrome patients? Methods This descriptive-analytical study was conducted on cardiac patients. All of the non-ST elevation acute coronary syndrome (NSTEACS) including non-ST elevation myocardial infarction (NSTEMI) and unstable angina patients included in the study. Then they divided into two groups: prolonged P-R interval and normal P-R interval. The patients who had a history of digoxin and calcium channel blocker use, using antiarrhythmic drugs, known valvular or congenital heart disease and connective tissue, unreadable P-R interval and cardiac block were excluded. Data were collected using the questionnaire consisted demographic data and clinical outcomes and a follow-up part was completed by one of the researchers. Results Finally, 248 patients completed the study. The results showed both of the two groups had significant differences in terms of the history of myocardial infarction (MI) (p = 0.018), the level of high-density lipoprotein (HDL) (p = 0.004), heart rate (p = 0.042), inverted T wave (p = 0.017), anterior ST- segment depression (p = 0.008), normal report of coronary angiography (CAG) (p = 0.003), three vessels disease (p = 0.043), left main lesion (p = 0.045) and SYNTAX score (p = 0.032) based on the CAG report. The results of six-month follow-up showed although, the frequency of ischemic stroke, coronary artery disease (CAD) and cardiovascular death were higher in prolonged P-R interval groups. The chi-square test showed this difference was statistically non-significant (p > 0.05). The multivariate logistic regression model revealed non-significant relationships between prolonged P-R interval and SYNTAX score, significant CAD, three-vessel disease, inverted T wave, anterior ST depression, heart rate and HDL. Conclusions Based on the results of our study the six-month follow-up showed non-significant outcomes. Further studies are recommended to assess the long-term outcomes.

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2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Translation of the document prepared by the Czech Society of Cardiology

Táborský¹,

Kautzner²,

Fedorco³

et al. 2022

Cor Vasa

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Prolonged PR Interval and Outcome in Cardiac Resynchronization Therapy

Cited by 3 publications

References 5 publications

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)

Can prolonged P-R interval predict clinical outcomes in non-ST elevation acute coronary syndrome patients?

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Translation of the document prepared by the Czech Society of Cardiology

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