Prevalence of Dyslipidemias in Three Regions in Venezuela: The VEMSOLS Study Results

Abstract

BackgroundThe prevalence of dyslipidemia in multiple regions of Venezuela is unknown. The Venezuelan Metabolic Syndrome, Obesity and Lifestyle Study (VEMSOLS) was undertaken to evaluate cardiometabolic risk factors in Venezuela.ObjectiveTo determine the prevalence of dyslipidemia in five populations from three regions of Venezuela.MethodsDuring the years 2006 to 2010, 1320 subjects aged 20 years or older were selected by multistage stratified random sampling from all households in five municipalities from 3 regions of Venezuela: Lara State (Western region), Merida State (Andean region), and Capital District (Capital region). Anthropometric measurements and biochemical analysis were obtained from each participant. Dyslipidemia was defined according to the NCEP/ATPIII definitions.ResultsMean age was 44.8 ± 0.39 years and 68.5% were females. The prevalence of lipids abnormalities related to the metabolic syndrome (low HDL-c [58.6%; 95% CI 54.9 - 62.1] and elevated triglycerides [39.7%; 36.1 - 43.2]) were the most prevalent lipid alterations, followed by atherogenic dyslipidemia (25.9%; 22.7 - 29.1), elevated LDL-c (23.3%; 20.2 - 26.4), hypercholesterolemia (22.2%; 19.2 - 25.2), and mix dyslipidemia (8.9%; 6.8 - 11.0). Dyslipidemia was more prevalent with increasing body mass index.ConclusionDyslipidemias are prevalent cardiometabolic risk factors in Venezuela. Among these, a higher prevalence of low HDL is a condition also consistently reported in Latin America.

Prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City, Northern Ethiopia

“…The prevalence of elevated triglyceride (40.2%) in this study is higher than the previous findings reported in Senegal (7.1%) [37], Nigeria (9.9%) [38], Ethiopia (21.0%) [30], and Malawi (28.7%) [39]. However, it is consistent with the study findings reported in Venezuela (39.7%) [40], Jordan (41.9%) [36], and Uganda (42.1%) [33]. But lower than the findings documented in Thailand (49.9%) [32], India (56.1%) [28], South Africa (59.3%) [19], and Brazil (65.3%) [41].…”

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

“…The prevalence of elevated total cholesterol in this study, 25.4% is almost consistent with the study findings reported in Venezuela, 22.2% [ 27 ], Nigeria, 23% [ 25 ], Durame, southern Ethiopia, 23.7% [ 15 ], and Africa, 25.5% [ 4 ]. Whereas, higher prevalence of elevated total cholesterol was reported in studies conducted in different parts of Ethiopia; Mekelle, 30.8% [ 18 ], Eastern Ethiopia, 33.7%, Hawassa, southern Ethiopia, 38.7% [ 16 ], and Togo, 64% [ 5 ].…”

“…The prevalence of elevated LDL-C in this study, 21.5% is comparable with the study findings reported in Hawassa, southern Ethiopia, 21% [ 16 ], Africa, 21.4% [ 4 ], India, 23% [ 22 ], and Venezuela, 23.3% [ 27 ]. However, it is higher than the study findings reported in China, 8.3% [ 1 ], Ethiopia, 14.1% [ 9 ], and India, 15.8% [ 29 ].…”

“…The most prevalent type of dyslipidemia was reduced HDL-C, 50.7% followed by elevated triglycerides, 33.4%, which is comparable with the findings from Ethiopia, [ 9 ], Iran [ 23 ], and Venezuela [ 27 ]. The prevalence of reduced HDL-C in this study, 50.7% is higher than the findings reported in Togo, 16.4% [ 5 ], Mekelle, 16.5% [ 18 ], China, 20.8% [ 1 ], and Durame, southern Ethiopia, 41.9% [ 15 ].…”

“…The prevalence of elevated triglyceride in this study, 33.4% is higher than the findings reported in Nigeria, 5% [ 25 ], Africa, 17% [ 4 ], Ethiopia, 21% [ 9 ], China, 22.5% [ 1 ], and India, 27% [ 22 ]. However, higher prevalence were reported in studies conducted in Venezuela, 39.7% [ 27 ], Mekelle, 40.2% [ 18 ], Saudi Arabia, 44% [ 7 ], and Hawassa, southern Ethiopia, 62.2% [ 16 ].…”