Cardiac Catheterization in a Patient with Obstructive Hypertrophic Cardiomyopathy
            and Syncope

Nunes, Rafael Amorim Belo; Ribeiro, Henrique Barbosa; Kajita, Luiz J.; Gaiotto, Fábio Antônio

doi:10.5935/abc.20170098

Cited by 2 publications

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“…The workup usually consists of imaging (CXR, thallium scan), Electrocardiography, echocardiography, Cardiac MRI, endocardial biopsy and cardiac catheterization in selected cases. [10] The management of cardiomyopathy is similar to treatment of congestive cardiac failure. Drug used to treat cardiomyopathy may include ACE inhibitors, Beta blockers, aldosterone antagonists, cardiac glycosides, diuretics and vasodilators.…”

Section: Introductionmentioning

confidence: 99%

Symptomatology and Clinical Features of Cardiomyopathy in Adults: A Prospective Study.

Vanjari¹,

Bhosale²,

Mali³

2018

AIMDR

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Background: Cardiomyopathies are diseases of heart muscle that result from myriad of insults such as genetic defects, cardiac myocyte injury, or infiltration of myocardial tissues. Cardiomyopathies result from insults to both cellular elements of the heart, notably the cardiac myocyte and processes that are external to cells such as deposition of abnormal substances into the extracellular matrix. Cardiomyopathies are traditionally defined on the basis of structural and functional phenotypes like dilated characterized primarily by an enlarged ventricular chamber and reduced cardiac performance, hypertrophic characterized by thickened hypertrophic ventricular walls and enhanced cardiac performance and restrictive characterized by thickened stiff ventricular walls that impede diastolic filling of the ventricle. The symptoms vary depending upon the type and severity of cardiomyopathy and may include fatigue, dyspnea, orthopnea and edema. The clinical features may include tachycardia, tachypnea, Raised JVP, pulmonary edema and hepatomegaly amongst others. We conducted this study to know the symptomatology and clinical features in adult patients diagnosed with cardiomyopathy. Aims and Objectives: To study the symptomatology and clinical Features of cardiomyopathy in adults. Methods: This was a prospective study of 50 patients of cardiomyopathy admitted in the medicine department of a tertiary care medical college situated in an urban area. The study was conducted after due approval from institutional ethical committee and obtaining informed consent from the patients. The patients were included in the study on the basis of predefined inclusion criteria. Patients having any exclusion criteria were excluded from the study. Symptomatology and clinical features of the patients were studied. The data was tabulated and analyzed using SPSS 16.0 version software. Results: The study consisted of 50 patients of cardiomyopathy out of which 26 (52%) were males and 24 (48%) were females with a M: F ratio of 1:0.92. Commonest types of cardiomyopathy was found to be dilated cardiomyopathy (46%) followed by ischemic cardiomyopathy (44%). More than 50% of the cases were found to be between the age group of 51 to 70 years. The most common symptoms in these patients were dyspnea (100%), chest pain (30%), Pedal Edema (30%) and palpitation (22%). Class III dyspnea was seen in 21 (42%) patients and class II dyspnea was seen in 18 (36%) patients. The most common Clinical feature seen in patients was found to be raised JVP (34%) followed by murmurs (32 %), basal crepts (32 %) and pedal edema (26 %). Conclusion: Cardiomyopathy is one of the important causes of morbidity and mortality in adult population. Early recognition and prompt management of cardiomyopathy will retard the progression of the disease and reduce morbidity and mortality in patients with cardiomyopathy.

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Section: Introductionmentioning

confidence: 99%

Symptomatology and Clinical Features of Cardiomyopathy in Adults: A Prospective Study.

Vanjari¹,

Bhosale²,

Mali³

2018

AIMDR

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A Narrative Review of Emerging Therapies for Hypertrophic Obstructive Cardiomyopathy

Menezes

Oliveira

Taia

et al. 2023

CCR

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Hypertrophic obstructive cardiomyopathy is a hereditary condition that affects myocardial contraction. In case of failure of pharmacological treatment, alternative approaches might be used that include surgical myectomy, percutaneous transluminal septal myocardial ablation, and radiofrequency ablation. In respect of long-term advantages, surgical septal myectomy remains the therapy of choice for symptomatic hypertrophic obstructive cardiomyopathy. Alcohol septal ablation has been considered an alternative to surgical myectomy, which confers the benefits of a shorter hospital stay, less discomfort, and fewer complications. However, only expert operators should perform it on carefully chosen patients. Further, radiofrequency septal ablation reduces the left ventricular outflow tract gradient and improves the NYHA functional class of patients with hypertrophic obstructive cardiomyopathy, despite complications like cardiac tamponade and atrioventricular block. Further research with a larger sample size is required to compare the radiofrequency approach with established invasive treatment methods for hypertrophic obstructive cardiomyopathy. Septal myectomy has low morbidity and mortality rates, making it the preferred procedure; however, the efficacy and morbidity remain debatable. Advances in invasive techniques, including percutaneous septal radiofrequency ablation and transcatheter myotomy, have provided alternative approaches for reducing left ventricular outflow tract (LVOT) obstruction in patients who are not candidates for traditional surgical septal myectomy. Candidates for alcohol and radiofrequency septal ablation include patients with symptomatic hypertrophic obstructive cardiomyopathy, older adults, and those with multiple comorbidities.

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Cardiac Catheterization in a Patient with Obstructive Hypertrophic Cardiomyopathy and Syncope

Cited by 2 publications

References 0 publications

Symptomatology and Clinical Features of Cardiomyopathy in Adults: A Prospective Study.

Symptomatology and Clinical Features of Cardiomyopathy in Adults: A Prospective Study.

A Narrative Review of Emerging Therapies for Hypertrophic Obstructive Cardiomyopathy

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