Diretrizes Brasileiras de Antiagregantes Plaquetários e Anticoagulantes em Cardiologia

Filho, Aristóteles Moreira; Azmus, AD; Soeiro, AM; Quadros, A M; Avezum, Álvaro; Marques, AC; Franci, André; Manica, ALL; Volschan, André; Paola, Aav de; Greco, A.-S. Jordan; ACN, Ferreira; Sousa, Acs; Pesaro, AEP; Simao, A.N.C; Lopes, ASSA; Timerman, Ari; Ramos, A. Molina; Alves, BR; Caramelli, Bruno; Mendes, BA; Polanczyk, Carísi Anne; Montenegro, C. A; Barbosa, CJDG; Serrano, C; Melo, CCL; Pinho, Claudio; Moreira, Dar; Calderaro, Daniela; Gualandro, DM; Armaganijan, Dikran; Neto, EA Machado; Bocchi, EA; Paiva, EF; Stefanini, Edson; D'Ámico, Elbio Antônio; Evaristo, EF; Silva, EER; Fernandes, Francisco Leonel F.; Brito, F. A. F.; Bacal, Fernando; Ganem, Fabiana; Gomes, F.P.; Mattos, FR; Neto, FR Moraes; Tarasoutchi, Flávio; Darrieux, FCC; Feitosa, GS; Fenelon, Guilherme; Morais, GR; Filho, Harry Correa; Castro, I; Gonçalves, Iran; Atié, Jacob; Neto, JD Souza; Ferreira, Jfm; Nicolau, José Carlos; Faria-Neto, José Rocha; Annichino-Bizzacchi, JM; Li, Zimerman; Piegas, L S; Pires, LJT; Baracioli, LM; Silva, LB; Mattos, LAP; Lisboa, L. S. S.; Magalhães, LPM; Lopes, M. Pinho; Montera, MW; Figueiredo, MJO; Malachias, Mvb; Gaz, MVB; Andrade, M N; Bacellar, MSC; Barbosa, MR; Clausell, NO; Dutra, OP; Coelho, OR; Yu, PC; Lavítola, PL; Neto, PA Lemos; Andrade, Pedro; Farsky, PS; Franco, R. Rodriguez; Kalil, RAK; Lopes, RD; Esporcatte, Roberto; Heinisch, RH; Filho, Roberto Kalil; Giraldez, RRCV; Alves, RC; Leite, REGS; Gagliardi, R. Coronel; Ramos, RF; Montenegro, ST; Accorsi, TAD; Jardim, Tsv; Scudeler, TL; Moisés, VA; Portal, VL

doi:10.5935/abc.2013s009

Cited by 30 publications

(15 citation statements)

References 360 publications

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“…The time between the accident and medical assistance in the state, as reported also in other regions of Brazil [ 28 ], was less than 3 hours in 69.6% of cases. Most of the severe cases (79.4%) also received treatment in less than 6 hours after the sting, probably contributing to preventing higher lethality in the Amazon.…”

Section: Discussionmentioning

confidence: 77%

Severity of Scorpion Stings in the Western Brazilian Amazon: A Case-Control Study

et al. 2015

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BackgroundScorpion stings are a major public health problem in Brazil, with an increasing number of registered cases every year. Affecting mostly vulnerable populations, the phenomenon is not well described and is considered a neglected disease. In Brazil, the use of anti-venom formulations is provided free of charge. The associate scorpion sting case is subject to compulsory reporting. This paper describes the epidemiology and identifies factors associated with severity of scorpions stings in the state of Amazonas, in the Western Brazilian Amazon.Methodology/Principal FindingsThis study included all cases of scorpion stings in the state of Amazonas reported to the Brazilian Diseases Surveillance System from January 1, 2007 to December 31, 2014. A case-control study was conducted to identify factors associated with scorpions sting severity. A total of 2,120 cases were reported during this period. The mean incidence rate in the Amazonas was 7.6 per 100,000 inhabitants/year. Scorpion stings showed a large spatial distribution in the state and represent a potential occupational health problem for rural populations. There was a positive correlation between the absolute number of cases and the altimetric river levels in the Central (p<0.001; Rs = 0.479 linear) and Southwest (p = 0.032; linear Rs = 0.261) regions of the state. Cases were mostly classified as mild (68.6%), followed by moderate (26.8%), and severe (4.6%). The overall lethality rate was 0.3%. Lethality rate among children ≤10 years was 1.3%. Age <10 years [OR = 2.58 (95%CI = 1.47–4.55; p = 0.001)], stings occurring in the rural area [OR = 1.97 (95%CI = 1.18–3.29; p = 0.033) and in the South region of the state [OR = 1.85 (95%CI = 1.17–2.93; p = 0.008)] were independently associated with the risk of developing severity.Conclusions/SignificanceScorpion stings show an extensive distribution in the Western Brazilian Amazon threatening especially rural populations, children ≤10 in particular. Thus, the mapping of scorpions fauna in different Amazon localities is essential and must be accompanied by the characterization of the main biological activities of the venoms. Urban and farming planning, in parallel with awareness of workers at risk for scorpion stings on the need for personal protective equipment use should be considered as public policies for preventing scorpionism.

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Section: Discussionmentioning

confidence: 77%

Severity of Scorpion Stings in the Western Brazilian Amazon: A Case-Control Study

et al. 2015

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“…However, at 24-hour, 48-hour, and 72-hour telephone follow-up, it was the complication least reported by patients. The literature suggests that the incidence of arterial access-related hematoma ranges from 0.1 to 9%, with hematomas graded as large if > 10cm or small if < 10cm 10 .…”

Section: Discussionmentioning

confidence: 99%

Reducing bed rest time from five to three hours does not increase complications after cardiac catheterization: the THREE CATH Trial

Matte

Hilário²,

Reich

et al. 2016

Rev. Latino-Am. Enfermagem

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Objective: to compare the incidence of vascular complications in patients undergoing transfemoral cardiac catheterization with a 6F introducer sheath followed by 3-hour versus 5-hour rest. Methods: randomized clinical trial. Subjects in the intervention group (IG) ambulated 3 hours after sheath removal, versus 5 hours in the control group (CG). All patients remained in the catheterization laboratory for 5 hours and were assessed hourly, and were contacted 24, 48, and 72 h after hospital discharge. Results: the sample comprised 367 patients in the IG and 363 in the GC. During cath lab stay, hematoma was the most common complication in both groups, occurring in 12 (3%) IG and 13 (4%) CG subjects (P=0.87). Bleeding occurred in 4 (1%) IG and 6 (2%) CG subjects (P=0.51), and vasovagal reaction in 5 (1.4%) IG and 4 (1.1%) CG subjects (P=0.75). At 24-h, 48-h, and 72-h bruising was the most commonly reported complication in both groups. None of the comparisons revealed any significant between-group differences. Conclusion: the results of this trial show that reducing bed rest time to 3 hours after elective cardiac catheterization is safe and does not increase complications as compared with a 5-hour rest. ClinicalTrials.gov Identifier: NCT-01740856

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“…18 The PT tests, used to provide the INR value, were conducted by a third-party laboratory, and blood samples were collected at home. According to both Brazilian 19 and international anticoagulation guidelines, 1,2,5 the therapeutic INR range recommended for the majority of indications is from 2.0 to 3.0. However, there are exceptions for some patients with prosthetic valves or patients with frequent thromboembolic events, who may need an INR value in the range of 2.5 to 3.5.…”

Section: Methodsmentioning

confidence: 99%

Nível de informação e adesão à terapia de anticoagulação oral com varfarina em pacientes acompanhados em ambulatório de atenção primária à saúde

2018

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Background: Oral anticoagulation therapy with warfarin is widely used around the world and its safety and efficacy are well-established. Nevertheless, anticoagulants are among the drug classes most associated with fatal medication errors in primary health care. Objective: To investigate patient knowledge, the level of information provided, and medication adherence in patients treated with warfarin at a primary health care service. Method: A cross-sectional study of a prospective cohort of 60 patients on warfarin treatment in the town of Ijuí, Rio Grande do Sul, Brazil. A questionnaire was administered to test patients' knowledge about their prescriptions and the level of information provided by the health team. The 8-item Morisky Medication Adherence Scale (MMAS-8) and International Normalized Ratio (INR) were used to verify adherence to treatment. Results: The results were expressed in absolute and relative values and prevalence ratios were calculated, with respective 95% confidence intervals. It was found that 83.3% of the participants had been given insufficient information by the health team, 50% did not know how to use the medication correctly, 86.7% were not adherent to the treatment according to MMAS-8 and 63.3% were outside of the correct INR range. Conclusion: In this study, we observed a need to improve the quality of information provided to users and to develop strategies to improve adherence to treatment, to ensure the safety of patients treated with warfarin in primary health care services.

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Diretrizes Brasileiras de Antiagregantes Plaquetários e Anticoagulantes em Cardiologia

Cited by 30 publications

References 360 publications

Severity of Scorpion Stings in the Western Brazilian Amazon: A Case-Control Study

Severity of Scorpion Stings in the Western Brazilian Amazon: A Case-Control Study

Reducing bed rest time from five to three hours does not increase complications after cardiac catheterization: the THREE CATH Trial

Nível de informação e adesão à terapia de anticoagulação oral com varfarina em pacientes acompanhados em ambulatório de atenção primária à saúde

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