Short and Long-Term Outcome of Stress-Induced Cardiomyopathy: What Can We Expect?

Ribeiro, Vania Filipa Andrade; Vasconcelos, Mariana; Melão, Filipa; Ferreira, Ester; Malangatana, Gracieta; Maciel, Maria Júlia

doi:10.5935/abc.20130228

Cited by 12 publications

(10 citation statements)

References 20 publications

(28 reference statements)

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“… 16–19 During the acute phase of TS, the clinical presentation is often described as indistinguishable from that of an acute myocardial infarction (AMI). 10 Chest pain followed by dyspnoea, 10 11 16–19 lipothymy with or without syncope 10 16 18 19 and malaise 16 is the most common clinical presentation for TS. Chest pain was more common in patients with a myocardial infarction than in those with TS, while dyspnoea, 10 16 syncope and malaise were more common in patients with TS.…”

Section: Introductionmentioning

confidence: 99%

Symptoms in patients with takotsubo syndrome: a qualitative interview study: Table 1

et al. 2016

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ObjectiveThe aim of the study was to investigate the meaning of narrated symptoms in connection to takotsubo syndrome.Design, method, participants and settingQualitative study consisting of 25 interviews, 23 women and 2 men aged 39–84 and living in Region Västra Götaland, Sweden. The transcribed text was analysed with phenomenological hermeneutics.ResultsThe interviewees reported a large number of symptoms before, during and after the acute onset of takotsubo syndrome, including pain, affected breathing, lassitude, malaise and nausea. Several of these have not been reported previously. Symptoms before the acute onset were, even if they had been prominent, ignored by the interviewees for various reasons. During the acute phase, the symptoms could no longer be ignored and the interviewees sought healthcare. The remaining residual symptom after discharge from hospital caused a great deal of worry because the interviewees feared that they would be permanent and they felt they could not live this way. On the whole, becoming ill and having a large number of symptoms greatly impacted the lives of the interviewees and made them re-evaluate how they had been living. Furthermore, they reported feeling alone and lost regarding their symptom burden, especially in relation to their residual symptoms, which affected their health and ability to return to daily life.ConclusionsAcute symptoms, and symptoms before and after the acute ones, are a major part of the illness experience for patients with takotsubo syndrome and affect their health and well-being. Assessment of symptoms should be an integrated part of care to promote health. One way of achieving this is through the patients’ own narratives of their experiences, which are an important component in person-centred care.

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Section: Introductionmentioning

confidence: 99%

Symptoms in patients with takotsubo syndrome: a qualitative interview study: Table 1

et al. 2016

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“…So far TTS was described as a benign reversible disease with a favourable outcome. Recently there has been some suspicion that TTS may have poorer outcome than has been assumed …”

Section: Discussionmentioning

confidence: 99%

“…Recently there has been some suspicion that TTS may have poorer outcome than has been assumed. 10 TTS may be associated with some critical complications such as heart failure, life-threatening arrhythmias, atrial fibrillation, QT-prolongation, thromboembolic events, the recurrence of TTS, left ventricular outflow obstruction, mitral valve regurgitation, and cardiac rupture. 11 It has also been reported that TTS is associated with cardiac fibrosis and inflammation.…”

Section: Discussionmentioning

confidence: 99%

Impact of T‐inversion on the outcome of Takotsubo syndrome as compared to acute coronary syndrome

Gietzen

El‐Battrawy

Lang

et al. 2019

Eur J Clin Investigation

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Background Previous studies revealed that patients with Takotsubo syndrome (TTS) have a higher mortality rate than the general population and a comparable mortality to acute coronary syndrome (ACS). Repolarisation abnormalities, namely T‐wave amplitude, may provide incremental prognostic information, in addition to traditional risk factors in ACS. This study was performed to determine the short‐ and long‐term prognostic impact of inverted T‐waves in TTS patients, as compared to ACS patients. Methods and results Our institutional database constituted a collective of 138 patients diagnosed with TTS from 2003 to 2017, as well as 532 patients suffering from ACS. Patients with TTS or with ACS (n = 138 per group) were matched for age and sex and assessed retrospectively and prospectively and divided into two groups, TTS with inverted T‐waves (n = 123) and ACS with inverted T‐waves (n = 80). In‐hospital complications such as respiratory failure with the need of respiratory support (60.2% vs 6.3%; P < 0.01), thromboembolic events (13.8% vs 2.5%; P < 0.01) and cardiogenic shock (18.9% vs 8.8%; P = 0.05) were significantly more presented in TTS as compared to ACS patients. Among cardiovascular risk factors diabetes mellitus (23.6% vs 45.0%; P < 0.01) and arterial hypertension (57.7% vs 78.8%; P < 0.01) were more presented in ACS patients as compared to TTS patients. Short‐term mortality was similar, however the long‐term mortality of 5 years was significantly higher in the TTS group (25.2% vs 7.5%; P < 0.01). In univariate analysis were male gender, EF < 35%, GFR < 60 mL/min, cardiogenic shock, inotropic drugs and history of cancer predictors of 5‐year mortality. The multivariate analysis showed only male gender (HR 2.7, 95% CI 1.1‐6.5; P = 0.02), GFR < 60 mL/min (HR 2.8, 95% CI 1.2‐6.0; P = 0.01) and history of cancer (HR 3.6, 95% CI 1.4‐9.3; P < 0.01) as independent predictors of 5‐year mortality. Conclusion Rates of long‐term mortality were significantly higher in TTS patients showing inverted T‐waves compared with patients diagnosed with ACS with inverted T‐waves. However, T‐inversion was not an independent predictor of 5‐year mortality in the multivariate analysis.

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“…Istnieje udokumentowany przypadek pacjentki, u której choroba wystąpiła 4-krotnie [7]. W więk-szości przypadków rokowanie jest korzystne, u niektórych chorych jednak dochodzi do groźnych powikłań, które mogą być nawet przyczyną zgonu [8][9][10][11][12][13][14].…”

Section: Wstępunclassified

Parametry echokardiograficzne wpływające na rokowanie pacjentów z kardiomiopatią takotsubo

Budnik

2017

Folia Cardiologica

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StreszczenieKardiomiopatia takotsubo to odwracalna dysfunkcja skurczowa lewej komory, której objawy przypominają ostry zespół wieńcowy. Rokowanie jest na ogół korzystne -w ciągu kilku tygodni dochodzi do poprawy funkcji skurczowej lewej komory, jednak czasami występują powikłania, takie jak ostra niedomykalność mitralna, dysfunkcja prawej komory, zawężanie drogi odpływu lewej komory, skrzeplina w lewej komorze, ostra niewydolność serca lub wstrząs kardiogenny, które mogą nawet prowadzić do zgonu. Dlatego niezwykle istotne jest znalezienie czynników, które wpływają na rokowanie pacjentów, a które są łatwo i szybko dostępne.Słowa kluczowe: takotsubo, zespół balotującego koniuszka, kardiomiopatia stresowa Cardiologica 2016; 11, 6: 569-574 Folia

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Short and Long-Term Outcome of Stress-Induced Cardiomyopathy: What Can We Expect?

Cited by 12 publications

References 20 publications

Symptoms in patients with takotsubo syndrome: a qualitative interview study: Table 1

Symptoms in patients with takotsubo syndrome: a qualitative interview study: Table 1

Impact of T‐inversion on the outcome of Takotsubo syndrome as compared to acute coronary syndrome

Parametry echokardiograficzne wpływające na rokowanie pacjentów z kardiomiopatią takotsubo

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