Impact of Ventricular Geometric Pattern on Cardiac Remodeling after Myocardial Infarction

Farah, E; Fusco, D.; Okumoto, Paulo R. R.; Minicucci, Marcos F.; Azevedo, Paula S.; Matsubara, Beatriz Bojikian; Okoshi, Katashi; Zanati, Silméia Garcia; Paiva, Sérgio Alberto Rupp de; Zornoff, Leonardo A. M.

doi:10.5935/abc.20130104

Cited by 2 publications

(5 citation statements)

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“…Clinical variables were obtained: age, gender, ethnicity, symptoms at admission, duration of chest pain (between the onset of pain and the first assessment in the emergency room), prior coronary revascularization, heart rate, systemic blood pressure and signs of pulmonary and systemic congestion 5-8 .…”

Section: Methodsmentioning

confidence: 99%

“…The following cardiovascular risk factors were investigated: systemic arterial hypertension (SAH), Diabetes Mellitus (DM), dyslipidemia, smoking, obesity and family history of coronary artery disease 5-8 .…”

Section: Methodsmentioning

confidence: 99%

“…Weight, height and waist circumference were measured in the morning, after fasting, 48 hours after admission with patients wearing the standard hospital gown 5-8 .…”

Section: Methodsmentioning

confidence: 99%

“…Regarding the treatment of AMI, reperfusion strategy and the following drugs prescribed during the in-hospital phase were evaluated: acetylsalicylic acid (ASA), Clopidogrel, heparin (unfractionated or low-molecular weight), Glycoprotein IIb/IIIa receptor inhibitor (IGP IIb/IIIa) inhibitors, angiotensin-converting enzyme inhibitors (ACEI), beta-blockers, calcium-channel blockers, nitrates, intravenous positive inotropic agents, diuretics, digitalis, statins, spironolactone and warfarin 5-8 .…”

Section: Methodsmentioning

confidence: 99%

“…The post-AMI clinical complications that occurred in the in-hospital phase were defined as follows: post-AMI ischemia as the occurrence of chest pain during appropriate drug therapy and/or acute ischemic alterations in the electrocardiogram (ECG) after the second day of evolution after AMI; arrhythmia with occurrence of sustained ventricular tachycardia or ventricular fibrillation; heart failure as clinical or radiological pulmonary congestion that required intravenous diuretic treatment, presence of hypotension as SBP < 90 mmHg for a period > 30 minutes in euvolemic patients with no signs of tissue hypoperfusion; cardiogenic shock, as SBP < 90 mmHg for a period > 30 min and signs of peripheral hypoperfusion (cold extremities, oliguria, sweating, pallor, restlessness or drowsiness) associated with pulmonary congestion and pericarditis, as occurrences of characteristic chest discomfort and associated with pericardial friction or the presence of diffuse ST-segment elevation on the electrocardiogram 5-8 .…”

Section: Methodsmentioning

confidence: 99%

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Infarct Size as Predictor of Systolic Functional Recovery after Myocardial Infarction

Minicucci¹,

Farah²,

Fusco³

et al. 2014

Arquivos Brasileiros De Cardiologia

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Background The effects of modern therapy on functional recovery after acute myocardial infarction (AMI) are unknown.ObjectivesTo evaluate the predictors of systolic functional recovery after anterior wall AMI in patients undergoing modern therapy (reperfusion, aggressive platelet antiaggregant therapy, angiotensin-converting enzyme inhibitors and beta-blockers).MethodsA total of 94 consecutive patients with AMI with ST-segment elevation were enrolled. Echocardiograms were performed during the in-hospital phase and after 6 months. Systolic dysfunction was defined as ejection fraction value < 50%.ResultsIn the initial echocardiogram, 64% of patients had systolic dysfunction. Patients with ventricular dysfunction had greater infarct size, assessed by the measurement of total and isoenzyme MB creatine kinase enzymes, than patients without dysfunction. Additionally, 24.5% of patients that initially had systolic dysfunction showed recovery within 6 months after AMI. Patients who recovered ventricular function had smaller infarct sizes, but larger values of ejection fraction and E-wave deceleration time than patients without recovery. At the multivariate analysis, it can be observed that infarct size was the only independent predictor of functional recovery after 6 months of AMI when adjusted for age, gender, ejection fraction and E-wave deceleration time.Conclusion In spite of aggressive treatment, systolic ventricular dysfunction remains a frequent event after the anterior wall myocardial infarction. Additionally, 25% of patients show functional recovery. Finally, infarct size was the only significant predictor of functional recovery after six months of acute myocardial infarction.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…Weight, height and waist circumference were measured in the morning, after fasting, 48 hours after admission with patients wearing the standard hospital gown 5-8 .…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Infarct Size as Predictor of Systolic Functional Recovery after Myocardial Infarction

Minicucci¹,

Farah²,

Fusco³

et al. 2014

Arquivos Brasileiros De Cardiologia

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Impact of Different Obesity Assessment Methods after Acute Coronary Syndromes

Nunes¹,

Minicucci²,

Farah³

et al. 2014

Arquivos Brasileiros De Cardiologia

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BackgroundAbdominal obesity is an important cardiovascular risk factor. Therefore, identifying the best method for measuring waist circumference (WC) is a priority.ObjectiveTo evaluate the eight methods of measuring WC in patients with acute coronary syndrome (ACS) as a predictor of cardiovascular complications during hospitalization. MethodsProspective study of patients with ACS. The measurement of WC was performed by eight known methods: midpoint between the last rib and the iliac crest (1), point of minimum circumference (2); immediately above the iliac crest (3), umbilicus (4), one inch above the umbilicus (5), one centimeter above the umbilicus (6), smallest rib and (7) the point of greatest circumference around the waist (8). Complications included: angina, arrhythmia, heart failure, cardiogenic shock, hypotension, pericarditis and death. Logistic regression tests were used for predictive factors. ResultsA total of 55 patients were evaluated. During the hospitalization period, which corresponded on average to seven days, 37 (67%) patients had complications, with the exception of death, which was not observed in any of the cases. Of these complications, the only one that was associated with WC was angina, and with every cm of WC increase, the risk for angina increased from 7.5 to 9.9%, depending on the measurement site. It is noteworthy the fact that there was no difference between the different methods of measuring WC as a predictor of angina. ConclusionThe eight methods of measuring WC are also predictors of recurrent angina after acute coronary syndromes.

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Impact of Ventricular Geometric Pattern on Cardiac Remodeling after Myocardial Infarction

Abstract: The LV geometric pattern of can have an impact on the remodeling process in patients with myocardial infarction.

Cited by 2 publications

References 28 publications

Infarct Size as Predictor of Systolic Functional Recovery after Myocardial Infarction

Infarct Size as Predictor of Systolic Functional Recovery after Myocardial Infarction

Impact of Different Obesity Assessment Methods after Acute Coronary Syndromes

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